A double helix-shaped optical fiber sensor for non-endoscopic diagnosis of gastrin-17

Wen, Hsin Yi; Weng, Yu-Qiao; Chen, Rou-Yu; Hsu, Hsiang-Cheng; Yeh, Yao‐Tsung; Chiang, Chia‐Chin

doi:10.1039/d2an00726f

Cited by 2 publications

(1 citation statement)

References 30 publications

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“…[5][6][7][8] Among the previously reported fiber-optic sensors, nanostructured sensors based on localized surface plasmon reso-nance (LSPR), i.e., a collective oscillation of free electrons in noble metal nanostructures, featuring high sensitivity to refractive index (RI) changes, are widely used in biosensing applications. [9][10][11][12] In order to achieve a low limit of detection (LOD) of biomolecules, numerous research works have been performed to optimize the configuration of plasmonic sensors. Different 2D and 3D nanostructures, such as nanospheres, nanorings, and nanocones, have been designed and integrated into the fiber tips by either top-down or bottom-up nanofabrication techniques.…”

Section: Introductionmentioning

confidence: 99%

A parylene-mediated plasmonic–photonic hybrid fiber-optic sensor and its instrumentation for miniaturized and self-referenced biosensing

Wang

et al. 2023

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Section: Introductionmentioning

confidence: 99%

A parylene-mediated plasmonic–photonic hybrid fiber-optic sensor and its instrumentation for miniaturized and self-referenced biosensing

Wang

et al. 2023

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Unpacking the packaged optical fiber bio-sensors: understanding the obstacle for biomedical application

Bissen,

Yunussova,

Myrkhiyeva

et al. 2024

Front. Bioeng. Biotechnol.

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A biosensor is a promising alternative tool for the detection of clinically relevant analytes. Optical fiber as a transducer element in biosensors offers low cost, biocompatibility, and lack of electromagnetic interference. Moreover, due to the miniature size of optical fibers, they have the potential to be used in microfluidic chips and in vivo applications. The number of optical fiber biosensors are extensively growing: they have been developed to detect different analytes ranging from small molecules to whole cells. Yet the widespread applications of optical fiber biosensor have been hindered; one of the reasons is the lack of suitable packaging for their real-life application. In order to translate optical fiber biosensors into clinical practice, a proper embedding of biosensors into medical devices or portable chips is often required. A proper packaging approach is frequently as challenging as the sensor architecture itself. Therefore, this review aims to give an unpack different aspects of the integration of optical fiber biosensors into packaging platforms to bring them closer to actual clinical use. Particularly, the paper discusses how optical fiber sensors are integrated into flow cells, organized into microfluidic chips, inserted into catheters, or otherwise encased in medical devices to meet requirements of the prospective applications.

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A double helix-shaped optical fiber sensor for non-endoscopic diagnosis of gastrin-17

Abstract: Non-endoscopic tools for the diagnosis evaluated for patients should be promoted in the biomedical assay as well as the need for highly sensitive, efficient, low-cost, and user-friendly sensors must be...

Cited by 2 publications

References 30 publications

A parylene-mediated plasmonic–photonic hybrid fiber-optic sensor and its instrumentation for miniaturized and self-referenced biosensing

A parylene-mediated plasmonic–photonic hybrid fiber-optic sensor and its instrumentation for miniaturized and self-referenced biosensing

Unpacking the packaged optical fiber bio-sensors: understanding the obstacle for biomedical application

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