A Double Wavelength Laser Doppler System to Investigate Skin Microcirculation

Duteil, L.; Bernango, Jean Claude; Schalla, W.

doi:10.1109/tbme.1985.325452

Cited by 54 publications

(25 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It currently appears that the red and infrared wavelengths, coupled with an appropriate separation of transmitter and receiver provide a larger contribution from deeper dermal structures [22,23], as AVAs. By using this LD config uration LD F showed no change when the skin was visibly blanched by topical corticosteroides [11], but when blue laser light was used a detectable reduction in LDF was seen [24]. Synchronous assessment of human skin microcirculation by LDF and capillaroscopy showed discrepancies, which can be interpreted as evidence that LD F records blood flow in vessels in addition to the superficial, nutritional capillaries [10], For these reasons it is suggested that LDF, used in areas richly supplied with AVAs partially measures AVA flow.…”

Section: Discussionmentioning

confidence: 94%

The influence of ulnar nerve blockade on skin microvascular blood flow*

Netten

Wollersheim

Gielen

et al. 1995

Eur J Clin Investigation

View full text Add to dashboard Cite

Abstract. Microvascular research is seriously ham pered by the great temporal and spatial variability of the measured skin blood flow and variation in sympa thetic vasomotor reflexes within and between persons. Therefore skin vasomotor reflexes were studied before and after ulnar nerve blockade within the same person, resulting in a temporal complete denervation of the fifth finger and partial denervation of the fourth finger. Skin temperature and laser Doppler flux (LDF) were registrated to measure predominantly arteriove nous shuntflow. Measurements were performed on the palmar tip of the second and fifth finger in nine healthy volunteers, at baseline, and during a sympa thetic reflex test (i.e. inspiratory gasp) and postural response test. Beat-to-beat digital blood pressure was recorded from the third and fourth finger by a Finapres device. Baseline capillary blood cell velocity (CBV) was measured at the nailfold of the second and the fifth finger. After ulnar blockade baseline skin temperature, LD F and CBV increased significantly, with respectively (mean ± SE) 3*2±0*9°C, 20*9 ±5*9 relative perfusion units and 0*79 ±0*40 m m " 1 s. The percentage LDF decrease of the fifth finger during inspiratory gasp was 48*2 ±5*3% before and 3*1 ±0-9% after blockade. The postural response test showed a decrease in LDF of the fifth finger with no significant difference before and after block ade, respectively 12*3 ±14*7% and 8*0±2*7%, while no difference was found in the increase in digital blood pressure in the denervated fourth finger compared to both the same finger before blockade and to the third non-blocked finger. It is concluded that ulnar nerve blockade enables the study of sympathetic skin vasomotor reflexes by comparison of a denervated and a non-denervated vascular bed within the same person. After ulnar blockade arteriovenous shunt flow as well as nutritional capillary blood flow increased significantly. Postural vasoconstrictor response is not abolished by ulnar blockade, suggesting that local regulatory mechanisms are more important.

show abstract

Section: Discussionmentioning

confidence: 94%

The influence of ulnar nerve blockade on skin microvascular blood flow*

Netten

Wollersheim

Gielen

et al. 1995

Eur J Clin Investigation

View full text Add to dashboard Cite

show abstract

“…To achieve some degree of depth-resolved perfusion monitoring, some authors have considered either using different wavelengths [32,33] or changing the source-todetector distance [34]. Since the optical absorption by blood and, to a smaller extent, the scattering level of the tissue differ significantly for green, red and infrared light, this may be utilized to measure the blood flow in tissue volumes of different size and depth.…”

Section: Depth Sensitivity In Ldfmentioning

confidence: 99%

Review of methodological developments in laser Doppler flowmetry

et al. 2008

View full text Add to dashboard Cite

show abstract

“…To achieve some degree of depth resolved perfusion monitoring, the concepts of using either different wavelengths [32,33] or changing the source to detector distance [34] have been considered. Since the optical absorption by blood and to a smaller extent the scattering level of the tissue differs significantly for green, red and infrared light this may be utilized to measure the blood flow in tissue volumes of different size in depth.…”

Section: Depth Sensitivity In Ldfmentioning

confidence: 99%