We study a separable Hilbert space of smooth curves taking values in the Segal–Bergmann space of analytic functions in the complex plane, and two of its subspaces that are the domains of unbounded non self-adjoint linear partial differential operators of the first and second order. We show how to build a Hilbert basis for this space. We study these first- and second-order partial derivation non-self-adjoint operators defined on this space, showing that these operators are defined on dense subspaces of the initial space of smooth curves; we determine their respective adjoints, compute their respective commutators, determine their eigenvalues and, under some normalisation conditions on the eigenvectors, we present examples of a discrete set of eigenvalues. Using these derivation operators, we study a Schrödinger-type equation, building particular solutions given by their representation as smooth curves on the Segal–Bergmann space, and we show the existence of general solutions using an Fourier–Hilbert base of the space of smooth curves. We point out the existence of self-adjoint operators in the space of smooth curves that are obtained by the composition of the partial derivation operators with multiplication operators, showing that these operators admit simple sequences of eigenvalues and eigenvectors. We present two applications of the Schrödinger-type equation studied. In the first one, we consider a wave associated with an object having the mass of an electron, showing that two waves, when considered as having only a free real space variable, are entangled, in the sense that the probability densities in the real variable are almost perfectly correlated. In the second application, after postulating that a usual package of information may have a mass of the order of magnitude of the neutron’s mass attributed to it—and so well into the domain of possible quantisation—we explore some consequences of the model.