A dual-color fluorescent biosensing platform based on WS2 nanosheet for detection of Hg2+ and Ag+

Zuo, Xianwei; Zhang, Huige; Zhu, Qian; Wang, Weifeng; Feng, Jie; Chen, Xingguo

doi:10.1016/j.bios.2016.05.044

Cited by 111 publications

(43 citation statements)

References 47 publications

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“…S7A). 1,40,41 In addition, there is also a very good linear relationship that at low concentrations the quenching of fluorescence follows to the classic SternVolmer relationship, as shown in Fig. S7B.…”

Section: Sensitive and Selective Recognition Of Hgmentioning

confidence: 69%

“…[1][2][3][4][5] Mercury ion (Hg 2+ ) posed a tremendous menace owing to its bioaccumulation, such as permanent damage and slow accumulation in the central nervous and endocrine systems. 6 Moreover, it can easily give rise to a wide variety of diseases, including prenatal brain damage, serious cognitive problems, motion disorders and Minamata disease.…”

Section: Introductionmentioning

confidence: 99%

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Fabrication of Water-soluble Fluorescent Polymeric Micelles for Selective Detection of Hg2+ in Blood Serum

et al. 2017

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In this study, amphiphilic diblock copolymers were designed and synthesized via the incorporation of reversible additionfragmentation chain transfer radical polymerization (RAFT) and a subsequent grafting technique. Subsequently, Hg 2+ -sensitive water-soluble fluorescent polymeric micelles (FNs) were prepared by a reprecipitation strategy. The spectroscopic characteristics demonstrate that the fluorescein isothiocyanate (FITC) was successfully linked into the polymer. Due to the promoted reaction of desulfurization cyclization by Hg 2+ , the fluorescence of fluorescein in FNs was obviously quenched. The as-prepared FNs showed admirable Hg 2+ -sensitivity (detection limit: 54 nM), excellent water-solubility and high selectivity. In addition, FNs were successfully used to determine Hg 2+ in blood serum. We expected that the as-prepared FNs could perform potential applications in imaging, sensing, and bioanalytic chemistry.

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Section: Sensitive and Selective Recognition Of Hgmentioning

confidence: 69%

Section: Introductionmentioning

confidence: 99%

Fabrication of Water-soluble Fluorescent Polymeric Micelles for Selective Detection of Hg2+ in Blood Serum

et al. 2017

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“…Besides MoS 2 nanosheets, other TMD nanosheets, such as WS 2 , TiS 2 and TaS 2 , could also be used as effective nanoquenchers in fluorescent sensing . For example, Yuan et al developed a one‐step sonication‐assisted exfoliation method to prepare water‐soluble WS 2 nanosheets as effective fluorescence quenchers for nucleic acid and protein detection (Figure b) .…”

Section: Tmd Nanosheets and Their Composite‐based Optical Sensorsmentioning

confidence: 99%

Recent Advances in Sensing Applications of Two‐Dimensional Transition Metal Dichalcogenide Nanosheets and Their Composites

Ping

Fan

Sindoro

et al. 2017

Adv Funct Materials

244

146

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of 18) 1605817As a newly emerging class of nanomaterials, 2D TMD nanosheets possess a unique layered structure and large surface areas, as well as outstanding physical, chemical, optical, and electronic properties, which holds great potential for applications in catalysis, [37] sensing, [38] optics, [39] and energy. [40] In this review, we will focus on the introduction of state of the art sensing applications for 2D TMD nanosheets and their composites. In particular, different sensing strategies together with signal-transducing mechanisms in sensors based on 2D TMD nanosheets and their composites are thoroughly discussed. Our aim is to demonstrate a complete concept in this rapidly emerging research area and to address basic knowledge, opportunities, and challenges in this promising field. We expect that more 2D TMD nanosheets and their composites, as well as more sensing strategies, will be explored in this research field, enabling the fabrication of more accurate sensing devices for practical applications. TMD Nanosheets and Their Composite-Based Electrochemical SensorsThe electrochemical method has been extensively recognized as a powerful tool for fast access to biochemical information in complex samples due to its easy operation, fast response, high sensitivity, and low cost. Inspired by the use of graphene as transducers in electrochemical sensors, [41][42][43] researchers have attempted to use 2D TMD nanosheets as a transducer layer. Their good conductivity, large surface area, fast electron transfer kinetics, high signal/noise ratio, and, more importantly, their feasibility for forming composites, make 2D TMD nanosheets attractive as for electrochemical sensors. [44][45][46][47][48][49][50] Table 1 summarizes the recent progress of electrochemical sensors based on 2D TMD nanosheets and their composites. TMD Nanosheets as a Transducer Layer in Electrochemical SensorsIn 2012, our group developed a single-layer TMD-nanosheetbased electrochemical sensor, in which a single-layer MoS 2nanosheet-modified glassy carbon electrode was directly used for selective detection of dopamine in the presence of uric acid Two-dimensional (2D) transition metal dichalcogenide (TMD) nanosheets, such as MoS 2 , WS 2 , etc., are attracting increasing interest due to their intriguing physical, chemical, electronic, and optical properties. Success in development of methods for large-scale production of 2D TMD nanosheets and their composites has given great potential for various novel applications. In this review, recent progress in sensing applications of 2D TMD nanosheets and their composites is introduced. Moreover, different sensing strategies and signal-transducing mechanisms for sensing devices based on 2D TMD nanosheets and their composites are also summarized and discussed.

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“…Motivated by graphene research, [ 12 ] 2D transition‐metal dichalcogenides (TMDs) have recently attracted much attention because of large specific surface area, excellent electrical conductivity, and remarkable catalytic properties. [ 13 ] WS 2 is one of the emerging TMDs, where W layers are sandwiched between two atomic layers of S to form S–W–S structures. [ 14 ] To date, WS 2 has been synthesized using several methods including mechanical exfoliation, [ 15 ] atomic layer deposition, [ 16 ] chemical vapor deposition, [ 17 ] solvothermal, [ 18 ] lithium‐based intercalation, [ 19 ] electrochemical depositions, [ 20 ] and hydrothermal synthesis.…”

Section: Introductionmentioning

confidence: 99%

“…Recently, Zuo et al demonstrated a dual‐color fluorescent biosensor using 2H‐WS 2 nanosheets with Hg 2+ and Ag + specific DNA probes. [ 13 ] The obtained LDRs for Hg 2+ and Ag + were 6.0–650.0 n m and 5.0–1000.0 n m with the limit of detection (LODs) of 3.3 n m and 1.2 n m , respectively. [ 13 ] Li et al reported the fluorescent detection of Hg 2+ using 2H‐WS 2 nanosheets with T7 exonuclease.…”

Section: Introductionmentioning

confidence: 99%

Metallic 1T Phase Tungsten Disulfide Microflowers for Trace Level Detection of Hg²⁺ Ions

Rahman

Maruf

Faisal

et al. 2020

Advanced Sustainable Systems

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Electrochemical sensors for mercury ion detection would ideally demonstrate wide linear detection ranges (LDRs), ultratrace sensitivity, and high selectivity. This work presents an electrochemical sensor based on metallic 1T phase tungsten disulfide (WS2) microflowers for the detection of trace levels of Hg2+ ions with wide LDRs, ultratrace sensitivity, and high selectivity. Under optimized conditions, the sensor shows excellent sensitivities for Hg2+ with LDRs of 1 nm–1 µm and 0.1–1 mm. In addition to this, the limit of detection of the sensor toward Hg2+ is 0.0798 nm or 79.8 pm, which is well below the guideline value recommended by the World Health Organization. The sensor exhibits excellent selectivity for Hg2+ against other heavy metal ions including Cu2+, Fe3+, Ni2+, Pb2+, Cr3+, K+, Na+, Ag+, Sn2+, and Cd2+. The thus‐obtained excellent sensitivity and selectivity with wide LDRs can be attributed to the high conductivity, large surface area microflower structured 1T‐WS2, and the complexation of Hg2+ ions with S2−. In addition to good repeatability, reproducibility, and stability, this sensor shows the practical feasibility of Hg2+ detection in tap water suggesting a promising device for real applications.

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A dual-color fluorescent biosensing platform based on WS2 nanosheet for detection of Hg2+ and Ag+

Cited by 111 publications

References 47 publications

Fabrication of Water-soluble Fluorescent Polymeric Micelles for Selective Detection of Hg2+ in Blood Serum

Fabrication of Water-soluble Fluorescent Polymeric Micelles for Selective Detection of Hg2+ in Blood Serum

Recent Advances in Sensing Applications of Two‐Dimensional Transition Metal Dichalcogenide Nanosheets and Their Composites

Metallic 1T Phase Tungsten Disulfide Microflowers for Trace Level Detection of Hg²⁺ Ions

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A dual-color fluorescent biosensing platform based on WS2 nanosheet for detection of Hg2+ and Ag+

Cited by 111 publications

References 47 publications

Fabrication of Water-soluble Fluorescent Polymeric Micelles for Selective Detection of Hg2+ in Blood Serum

Fabrication of Water-soluble Fluorescent Polymeric Micelles for Selective Detection of Hg2+ in Blood Serum

Recent Advances in Sensing Applications of Two‐Dimensional Transition Metal Dichalcogenide Nanosheets and Their Composites

Metallic 1T Phase Tungsten Disulfide Microflowers for Trace Level Detection of Hg2+ Ions

Contact Info

Product

Resources

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Metallic 1T Phase Tungsten Disulfide Microflowers for Trace Level Detection of Hg²⁺ Ions