Isolated multiport DC/DC converters (MPC) are functional solutions for integrating renewable energy sources, increasing the efficiency of power distribution, and reinforcing DC grids. Although the concept of MPC has been proposed for past two decades, the applications of the MPC are upgrading as development of DC grids. The various MPC topologies have been proposed in previous work. This paper presents an overview about the topology of isolated MPCs applied in DC grids. This paper is dedicated to provide the comprehensive insights in isolated MPCs according to three main aspects in terms of converter configuration, potential application, and control feasibility. According to different applications, this paper classifies MPCs into three categories, including two-level MPC, three-level MPC, and multi-level MPC. Two different configurations of MPCs, multi-winding transformer type and multi-transformer type are discussed. In addition, a comparative analysis is performed in terms of circuit and operation conditions. The key technique problems and potential solutions are discussed. Finally, the future trends for the development of MPC are discussed. Keywords-DC/DC converter, DC grids, modular multilevel converter (MMC), neutral-point clamped (NPC) converter, multiport converter, isolated DC/DC converter.