A dynamic multibody model of the physiological knee to predict internal loads during movement in gravitational field

Bersini, Simone; Sansone, Valerio; Frigo, C.

doi:10.1080/10255842.2015.1051972

Cited by 22 publications

(29 citation statements)

References 34 publications

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“…The simulated knee forces in this article were quite close to the experimental results (cyan dash lines) obtained by Stylianou et al 32 until 60°knee flexion. Above that flexion level, the results tended to be much closer to experimental data (black dash lines) reported by Taylor et al 33 The results in this article were also generally consistent with the results calculated by Bersini et al 34 The results for the STKI are shown as black dotted lines in Figure 7. Above 50°knee flexion, the STKI resulted in smaller TF compressive forces than the CTKI.…”

Section: Resultssupporting

confidence: 91%

“…Above that flexion level, the results tended to be much closer to experimental data (black dash lines) reported by Taylor et al 33 . The results in this paper were also generally consistent with the results calculated by Bersini et al 34 . The results for the STKI are shown as black dotted lines in Fig.…”

Section: Figsupporting

confidence: 93%

“…The elongation variations of the ACL in the CTKI were generally consistent with the results of literature. 34,[38][39][40] Although the PCL does not contribute to the knee squat motion due to its negative initial pre-strain and the femoral posterior translation during squat, it is still important for other activities such as walking and stair-climbing in leg-sway phase.…”

Section: Discussionmentioning

confidence: 99%

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Preliminary study of a customised total knee implant with musculoskeletal and dynamic squatting simulation

Wang

2019

Proc Inst Mech Eng H

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Customised total knee replacement could be the future therapy for knee joint osteoarthritis. A preliminary design of a customised total knee implant based on knee anatomy was studied in this article. To evaluate its biomechanical performance, a dynamic finite element model based on the Oxford knee rig was created to simulate a squatting motion. Unlike previous research, this dynamic model was simulated with patient-specific muscle and joint loads that were calculated from an OpenSim musculoskeletal model. The dynamic response of the customised total knee implant was simulated under three cruciate ligament scenarios: both cruciate ligaments retained, only anterior cruciate ligament removed and both cruciate ligaments removed. In addition, an off-the-shelf symmetric total knee implant with retained cruciate ligaments was simulated for comparison analysis. The customised total knee implant with both cruciate ligaments retained showed larger ranges of femoral external rotation and posterior translation than the symmetric total knee implant. The motion of the customised total knee implant was also in good agreement with a healthy knee. There were no big differences in the tibiofemoral compressive forces in the customised total knee implant model under the three scenarios. These forces were generally consistent with other experimental and simulation results. However, the customised total knee implant design resulted in larger tibiofemoral compressive force than the symmetric total knee implant after 50° knee flexion, which was caused by the larger tibiofemoral relative motion.

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Section: Resultssupporting

confidence: 91%

Section: Figsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

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Preliminary study of a customised total knee implant with musculoskeletal and dynamic squatting simulation

Wang

2019

Proc Inst Mech Eng H

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“…As the Authors known, no studies addressed this topic and when the knee arthritis is localised at only one knee compartment, the surgical choice is generally driven by the orthopaedic surgeon experience. Results of Bersini 21 , that showed as the anterior fibres of ACL become inactive after 60° of knee flexion in conjunction with posterior cruciate ligament anterior bundle activation were deemed for the present study, relevant to suppose different strategies of squatting between TKA and UKA due to the different knee physiology, arthroplasty-related.…”

Section: Discussionmentioning

confidence: 99%

Assessment of patient functional performance in different knee arthroplasty designs during unconstrained squat

Verdini

Zara

Leo

et al. 2017

MLTJ

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SummaryBackground: In this paper, squat named by Authors unconstrained because performed without constrains related to feet position, speed, knee maximum angle to be reached, was tested as motor task revealing differences in functional performance after knee arthroplasty. It involves large joints ranges of motion, does not compromise joint safety and requires accurate control strategies to maintain balance. Methods: Motion capture techniques were used to study squat on a healthy control group (CTR) and on three groups, each characterised by a specific knee arthroplasty design: a Total Knee Arthroplasty (TKA), a Mobile Bearing and a Fixed Bearing Unicompartmental Knee Arthroplasty (respectively MBUA and FBUA). Squat was analysed during descent, maintenance and ascent phase and described by speed, angular kinematics of lower and upper body, the Center of Pressure (CoP) trajectory and muscle activation timing of quadriceps and biceps femoris. Results: Compared to CTR, for TKA and MBUA knee maximum flexion was lower, vertical speed during descent and ascent reduced and the duration of whole movement was longer. CoP mean distance was higher for all arthroplasty groups during descent as higher was, CoP mean velocity for MBUA and TKA during ascent and descent. Conclusions: Unconstrained squat is able to reveal differences in the functional performance among control and arthroplasty groups and between different arthroplasty designs. Considering the similarity index calculated for the variables showing statistically significance, FBUA performance appears to be closest to that of the CTR group. Level of evidence: III a.KEY WORDS: angular kinematics, Center of pressure, electromyography, unconstrained squat, unicompartmental knee arthroplasty, total knee arthroplasty.

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“…It is to be taken into account that neglection of deformations in some applications (e.g. simulation of implant-bone micromotions) might represent an unacceptable approximation, but nonetheless several outputs of interest in orthopedic applications (such as implant kinematics and contact forces) do not require a fully deformable model [5] : this method could thus represent a viable path to achieve the fast and overall accurate simulation tool sought, and it is indeed already used in many other engineering fields [6][7][8][9][10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Development and validation of an in-silico virtual testing rig for analyzing total knee arthroplasty performance during passive deep flexion: A feasibility study

Bori

Innocenti

2020

Medical Engineering & Physics

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The use of in-silico finite element (FE) models has become more common in orthopedic applications and in the design of biomedical devices, since they can provide results comparable to in vitro experiments while maintaining lower cost. The main downside of this kind of analysis is the high computing time, as it can reach hours or even days to complete; this limitation makes it then not suitable for time-sensitive applications, such as probabilistic analyses or helping clinicians in surgical pre-planning or intra-operative setting. In-silico multibody (MB) simulations, on the other hand, are significantly faster than FE simulations (considering each component of the model as a rigid body); although deformability of each model component is a necessary feature in some applications (e.g. simulation of implant-bone micromotions), several outputs of interest in orthopedic applications, such as implant kinematics and contact forces, do not require a fully deformable model. Therefore, this feasibility study aimed to develop a MB model of a human knee joint implanted with a Total Knee Arthroplasty; a 10 second flexion movement up to 105 °was then simulated and the results compared with validated FE models results (under similar boundary conditions) from literature, to perform a preliminary validation in terms of kinematic and kinetic results between the two methods. The agreement and relatively low computing time obtaining with this approach represent a promising starting point for subsequent studies and applications of such techniques in the clinical field.

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A dynamic multibody model of the physiological knee to predict internal loads during movement in gravitational field

Cited by 22 publications

References 34 publications

Preliminary study of a customised total knee implant with musculoskeletal and dynamic squatting simulation

Preliminary study of a customised total knee implant with musculoskeletal and dynamic squatting simulation

Assessment of patient functional performance in different knee arthroplasty designs during unconstrained squat

Development and validation of an in-silico virtual testing rig for analyzing total knee arthroplasty performance during passive deep flexion: A feasibility study

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