A eficácia da sacarose no alívio de dor em neonatos: revisão sistemática da literatura

Abstract

Objective: To present a review of empirical studies published from 1993 to 2004 on the efficacy of sucrose solution for relieving pain in neonates.Sources of data: Information was obtained from the MEDLINE/PsycINFO/ISI WEB of SCIENCE/LILACS and SciELO databases by searching for sucrose, pain, newborn and neonate. Summary of data:Sucrose solution has demonstrated efficacy in pain relief during puncture procedures on samples of preterm and fullterm neonates. The recommendation is to administer oral sucrose, to the front of the tongue, 2 minutes before the painful procedure. Other non-pharmacological interventions, such as human breastmilk via nasogastric tube, non-nutritional suckling and being held at the breast, also demonstrated synergic analgesic effects when administered in association with sucrose. The majority of studies demonstrated a positive pain relief effect with a single 2 ml dose at 25%. Conclusions could not be drawn on the best repeat administration scheme; in the few studies that did provide an indication, the dose was 0.1 ml at 24%. The analgesic pain relief effect promoted by the sucrose was observed through altered behavioral responses, facial activity and crying. Heart rate underwent larger reductions as a result of sucrose administration during painful procedures than any of the other physiological responses. Conclusions

Aspiração traqueal e dor: reações do recém-nascido pré-termo durante o cuidado

“…O manejo da dor aumenta a homeostase e a estabilidade dos RNs, sendo essencial para o cuidado e o suporte aos neonatos imaturos para poderem enfrentar o estresse da UTIN (17) . Um estudo realizado em 2008 com objetivo de avaliar o efeito da manobra de contenção durante a aspiração traqueal observou que este cuidado promove conforto, estabilização clínica e redução da dor nos neonatos (18) .…”

Investigação de um sistema de alimentação em recém-nascidos prematuros a partir de estimulação gustativa

“…Sucrose is widely used as non-pharmacological measure to control pain [9][10][11] and although this is not the purpose of this study, it is worth mentioning the fact that the Ministry of Health 7 propose the use of this substance in its protocols, somehow could facilitate the indication the pleasurable gustatory securely, since we already were attested to in the statement characterized population.…”

“…Strategies to promote breastfeeding are important to ensure the survival of the human species, since this favors immunity, digestion and absorption of nutrients [7][8][9][10][11][12][13][14][15][16][17][18][19][20] , but above all, in the speech area, this promotion may aid the development of the structures of the sensorial system motor oral (lips, tongue, cheeks, hard and soft palate), providing a better functioning of the functions stomatognatics [21][22][23][24] .…”

Efeitos da estimulação gustativa nos estados comportamentais de recém-nascidos prematuros

“…However, despite the potential damage caused by this environment, it is essential to monitor the premature newborn (9)(10)(11)(12)(13)(14) . In the presence of these stressful impacts, some authors (4,(15)(16)(17)(18)(19)(20)(21)(22) refer about the usage of sucrose as a measured nonpharmacological tool, observing that this substance has an analgesic effect and thus soothing. The sucrose was also used in research for speech, language and hearing sciences (2,23) , becoming evident as eliciting behavioral readiness upon feeding, particularly in alertness behavioral state, considered favorable (3) .…”