2021
DOI: 10.1016/j.impact.2020.100276
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A European nano-registry as a reliable database for quantitative risk assessment of nanomaterials? A comparison of national approaches

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Cited by 25 publications
(17 citation statements)
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“…If the production or import volume is >10 tons, >100 tons, or >1000 tons per year, an increasing number of additional toxicity tests are required for hazard and exposure assessment according to REACH [ 45 ]. It has to be highlighted, for nanomaterials, which are defined by the size range between 1–100 nm, more safety-relevant information is needed for the REACH registration [ 46 ]. These considerations are important for tracer substances that are still in the research and development (R&D) pipeline, as such substances would most probably exceed these REACH regulatory thresholds in the case of industry-scale implementation of plastic markers and would consequently require updates of information for the REACH registration.…”
Section: Methodological Approach For Tracer Selectionmentioning
confidence: 99%
“…If the production or import volume is >10 tons, >100 tons, or >1000 tons per year, an increasing number of additional toxicity tests are required for hazard and exposure assessment according to REACH [ 45 ]. It has to be highlighted, for nanomaterials, which are defined by the size range between 1–100 nm, more safety-relevant information is needed for the REACH registration [ 46 ]. These considerations are important for tracer substances that are still in the research and development (R&D) pipeline, as such substances would most probably exceed these REACH regulatory thresholds in the case of industry-scale implementation of plastic markers and would consequently require updates of information for the REACH registration.…”
Section: Methodological Approach For Tracer Selectionmentioning
confidence: 99%
“…Conceptualisation, characterisation techniques, toxicity/ecotoxicity tests, and even synthesis methods are still not homologated among countries. 191 Concerning the NM and NP concept, while it is true there is an agreement with the size ranges from 1 to 100 nm, there may be some variations such as the number of dimensions less than 100 nm, accumulation, and if they are biologically active or not, their solubility and even their biopersistence. Thus, Table 4 compiles NM denitions according to four organisms, where slight variations are translated in the rst challenge for applying regulations to nanotechnological products.…”
Section: Challenges and Advances Towards A Standardised Regulatory Pr...mentioning
confidence: 99%
“…Thus, regulation of nanomaterials and nanotechnology is of utmost importance. In particular, it is imperative to regulate the production, handling and use of nanoparticles and nanomaterials, either by legislation or simply by guidelines and recommendations [167,168]. A critical review on the migration potential of nanoparticles in food contact plastics was provided by [169].…”
Section: Safety and Regulatory Issuesmentioning
confidence: 99%