A European perspective on nosocomial urinary tract infections I. Report on the microbiology workload, etiology and antimicrobial susceptibility (ESGNI–003 study)

Bouza, Emilio; Juan, Rafael San; Muñóz, Patricia; Voss, A.; Kluytmans, Jan

doi:10.1046/j.1198-743x.2001.00326.x

Cited by 156 publications

(86 citation statements)

References 35 publications

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“…1,11 In contrast to community-acquired UTI, in which Escherichia coli is the single most common pathogen, the aetiological diversity (with no particularly predominant uropathogens) in CA-UTI leads to difficulty in predicting aetiological micro-organisms. 4,12 Recent reviews on nosocomial UTI have suggested that patients should be empirically treated with a cephalosporin or a penicillin/b-lactamase inhibitor with antipseudomonal activity, a carbapenem, a fluoroquinolone, aztreonam, or an aminoglycoside. 11,13 All of these regimens were mainly targeted at Gram-negative rod or nonfermenter infections.…”

Section: Discussionmentioning

confidence: 99%

“…In contrast to community-acquired, uncomplicated UTI, a wide variety of micro-organisms have been isolated from patients with CA-UTI. 3,4 In addition, because uropathogens in CA-UTI tend to show high rates of antibiotic resistance, the selection of appropriate empirical antibiotic treatment may be difficult. 5,6 Until microbiological results are available, appropriate selection of antibiotics for CA-UTI depends on known susceptibility patterns of suspected bacterial uropathogens, with third-generation cephalosporins or fluoroquinolones being used for enteric Gram-negative rods, ceftazidime for nonfermenters, ampicillin or vancomycin for enterococci, and methicillin for staphylococci.…”

Section: Introductionmentioning

confidence: 99%

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Factors associated with specific uropathogens in catheter-associated urinary tract infection: Developing a clinical prediction model

Hur

Kim

et al. 2014

J Int Med Res

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Objectives: To identify characteristics associated with particular groups of uropathogens in catheter-associated urinary tract infection (CA-UTI) and to develop clinical prediction rules for identifying these groups. Methods: Demographic, clinical and microbiological data were analysed from patients with CA-UTI. Infections were categorized into enteric Gram-negative rods, nonfermenters, Gram-positive cocci and fungal. Variables were analysed using univariate and multiple logistic regression analyses, and were used to develop clinical prediction rules. Results: A total of 492 patients were included in the study. Candida species were the most common uropathogens (30.7%), followed by enterococci (17.3%), Escherichia coli (12.0%), Pseudomonas spp. (10.8%), Klebsiella spp. (7.9%) and staphylococci (6.5%). Clinical prediction rules for the bacterial uropathogenic groups showed poor-to-fair discriminatory power, with sensitivities of <40% and specificities of >90%. However, clinical prediction rules showed good discriminatory power for fungal infections, with a sensitivity of 67.3% and a specificity of 78.1%. Conclusions: Clinical prediction rules developed for identifying specific groups of bacterial uropathogens in patients with CA-UTI had a low sensitivity, whereas those for fungal infections

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Factors associated with specific uropathogens in catheter-associated urinary tract infection: Developing a clinical prediction model

Hur

Kim

et al. 2014

J Int Med Res

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“…Kısa süreli (30 gün altında) sonda uygulanma oranı %90.8 olarak saptanmıştır. Sonda uygulanma süresi vakaların %44.8'inde 1-7 gün, %46'sındaysa 8-30 gündür (5).…”

Section: Epidemiyolojiunclassified

Catheter-Associated Urinary Tract Infections

Keten¹,

Aktaş²

2015

Klimik Dergisi

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ÖzetHastanede yatan hastalarda, invazif alet kullanımının artması, bozulmuş konak savunma mekanizmaları, altta yatan hastalıklar ve geniş spektrumlu antimikrobiyal kullanımına bağlı olarak, sağlık bakımıyla ilişkili infeksiyonlar daha sık görülmektedir. Sondayla ilişkili üriner sistem infeksiyonlarına neden olan mikroorganizmalar, sıklıkla endojen floradan kaynaklanmaktadır. Bu patojenler hastanın (kolon, vagina, meatus vb.) kendi florasından kaynaklanabileceği gibi, hastanede yatan olgularda sağlık çalışanlarının elleri veya kontamine aletlerle de bulaşma söz konusu olabilmektedir. Uygulanacak sondaların özellikleri, uygulama koşulları, uygulama sonrası bakım ve uygulamayı yapanların bilgi düzeyi, sondaya bağlı infeksiyon geliş-me riskini etkilemektedir. Bu yazıda sondayla ilişkili üriner sistem infeksiyonlarının, epidemiyolojisi, etyolojisi, patogenezi, risk faktörleri, sonda uygulamalarının çeşitleri, tanısı, tedavisi, prognozu ve önlen-mesi gözden geçirilmiştir. Klimik Dergisi 2014; 27(2): 38-47.Anahtar Sözcükler: Üriner sistem infeksiyonları, üriner sonda kullanımı, üriner sondayla ilişkili infeksiyonlar. AbstractHealthcare-associated infections are more frequently seen in hospitalized patients due to increased use of invasive techniques, impaired host immune system, comorbidities, and use of broad-spectrum antibiotics. Microorganism causing catheter-associated urinary tract infections may arise from patients' endogenous flora (colon, vagina, meatus etc.) or from contamination by staff during instrumentation. The risk of catheter-associated urinary tract infections are affected by properties of catheters, conditions of practice, post-practice care, and experience of the practitioner. This review outlines the epidemiology, etiology, pathogenesis, risk factors, catheterization techniques, diagnosis, therapy and prognosis of catheter-associated urinary tract infections, and preventive measures against these infections.

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“…National and international surveillance programmes are necessary to monitor the level of antimicrobial resistance [2]. According to the data obtained in a questionnaire from 228 hospitals in 29 European countries, the most frequent pathogen was identified as E.coli (35.6%), where 54.8% of isolates were resistant to ampicillin, 28% to co-trimoxazole and 9% to ciprofloxacin [3]. Alarmingly, significant ampicillin resistance (72.6%), cotrimoxazole resistance (77.9%) and norfloxacin resistance (78.4%) in E.coli strains were also reported [4].…”

Section: Introductionmentioning

confidence: 99%

Cross-resistance and associated resistance in Escherichia coli isolates from nosocomial urinary tract infections between 2004–2006 in a Turkish Hospital

et al. 2008

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AbstractIn this study, antimicrobial resistance profiles were determined for 748 isolates of Escherichia coli from patients with acute nosocomial urinary tract infections (UTIs) at a Turkish Training Hospital. Thirteen antibiotics were included. Resistance to ampicillin alone (45.1%) and ciprofloxacin alone (20.6%) were the most commonly identified ‘single resistances’. Multiple resistance was found in 49.7% of the strains. The most common multiple antibiotic resistance profiles included ampicillin-sulbactam/amoxycilline-clavulonate (4.0%) and ampicillin-sulbactam/trimethoprim-sulfamethoxazole/amoxycilline-clavulonate (2.8%). From 2004 to 2006, ampicillin, trimethoprim-sulfamethoxazole and ciprofloxacin resistant strains increased to 76% from 57%, 53% from 43% and 55% from 41%, respectively. The percentage of extended-spectrum β-lactamase (ESBL) producing strains was 7.8% and imipenem resistance was seen in 5.2% of ESBL positive strains. We conclude that clinically important E.coli strains have now emerged with broader multidrug resistance. Periodical evaluation of laboratory results and clinical surveillance are crucially important for optimal antibiotic management of UTIs and infection control policies.

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A European perspective on nosocomial urinary tract infections I. Report on the microbiology workload, etiology and antimicrobial susceptibility (ESGNI–003 study)

Cited by 156 publications

References 35 publications

Factors associated with specific uropathogens in catheter-associated urinary tract infection: Developing a clinical prediction model

Factors associated with specific uropathogens in catheter-associated urinary tract infection: Developing a clinical prediction model

Catheter-Associated Urinary Tract Infections

Cross-resistance and associated resistance in Escherichia coli isolates from nosocomial urinary tract infections between 2004–2006 in a Turkish Hospital

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