A facile 1,5-rearrangement of β-formylenamides and cleavage of esters catalysed by Pseudomonas fluorescens

Resolution of racemic 1-arylethyl acetates by Pseudomonas fluorescens in the presence of a surfactant

“…11 Recently we have demonstrated that the whole-cell-catalysed reaction of P. fluorescens RRLJ 134 can be successfully applied to the hydrolysis of acetates into symmetrical alcohols. 12 Herein, we report the use of P. fluorescens RRLJ 134 in the hydrolytic kinetic resolution of (R/S)-1-arylethyl acetates with a slight preference for the S-alcohol. We further demonstrate that the enantioselectivity of the bio-catalyst can be completely reversed and significantly enhanced by using the surfactant Tween-80.…”