A facile method for preparation of emulsion using the high gravity technique

Li, Yan; Mei, Ran Andy; Yang, Zhongqiang

doi:10.1016/j.jcis.2017.06.035

Cited by 10 publications

(6 citation statements)

References 47 publications

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“…40−42 The fluids in an RPB are torn into diminutive liquid droplets, lathy liquidus, or thin films under the intense shear force and porous packing. 43 This technology has been applied in nanoparticle preparation, 44,45 layer-by-layer selfassembly, 46,47 polymerization reaction, 48,49 as well as the emulsification field. 50,51 Herein, we report a high-gravityassisted process to efficiently fabricate pH-stimuli-responsive colloidosomes with a high EE.…”

Section: ■ Introductionmentioning

confidence: 99%

“…High-gravity technology is an efficient technique of process intensification, implemented in a rotating packed bed (RPB) for significantly enhancing molecular mixing and mass transfer processes. − The fluids in an RPB are torn into diminutive liquid droplets, lathy liquidus, or thin films under the intense shear force and porous packing . This technology has been applied in nanoparticle preparation, , layer-by-layer self-assembly, , polymerization reaction, , as well as the emulsification field. , Herein, we report a high-gravity-assisted process to efficiently fabricate pH-stimuli-responsive colloidosomes with a high EE.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Efficient Construction of pH-Stimuli-Responsive Colloidosomes with High Encapsulation Efficiency

Jia,

Liu,

Sun

et al. 2023

Langmuir

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Section: ■ Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Efficient Construction of pH-Stimuli-Responsive Colloidosomes with High Encapsulation Efficiency

Jia,

Liu,

Sun

et al. 2023

Langmuir

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“…38 The fluid in an RPB is torn into diminutive liquid droplets, lathy liquidus, or thin films under the enormous shear force and porous packing. 39 Thus, an RPB normally has the advantages of high efficiency, energy saving, transient residence duration and widespread applications. Currently, the high-gravity technology has been used for nanoparticle preparation, 40−42 polymerization reaction, 43,44 and layer-by-layer self-assembly.…”

Section: Introductionmentioning

confidence: 99%

“…A rotating packed bed (RPB) can usually be adopted to create a high-gravity surrounding, which is 1–3 orders of magnitude larger than that of Earth . The fluid in an RPB is torn into diminutive liquid droplets, lathy liquidus, or thin films under the enormous shear force and porous packing . Thus, an RPB normally has the advantages of high efficiency, energy saving, transient residence duration and widespread applications.…”

Section: Introductionmentioning

confidence: 99%

High-gravity-assisted Fabrication of Self-assembled Colloidosomes

Jia

Liu

et al. 2022

Ind. Eng. Chem. Res.

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Colloidosomes are widely applied in drug delivery systems on account of their outstanding biocompatibility and stimuli response. Herein, a novel and environmentally friendly approach is presented for efficiently fabricating colloidosomes by high-gravity technology, which is not only favorable for controllable latex particle size and large-scale production but also makes it avoidable to use a great deal of organic solvents. First, the latex particles as shell materials with a range of 47–62 nm are controllably prepared using high-gravity-assisted pre-emulsification for emulsion polymerization. Because of this pre-emulsification, the polymerization time is greatly shortened from 4 to 1 h, and the mean particle diameter is reduced by about 29%. In addition, the self-assembly of latex particles forming into colloidosomes is achieved using high-gravity technology. Compared with the preparation process in a conventional high-speed shearing machine, the colloidosomes prepared with the high-gravity self-assembly process have a decreased size of 3.5 to 2 μm and a narrower size distribution. Furthermore, an anticancer drug of doxorubicin hydrochloride is in situ encapsulated into the colloidosomes, displaying excellent controllable release properties.

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“…In addition, as a type of continuous reactor, the reactants pumped into the RPB are continuously added, followed by the continuous flow of products. The quality of the products is more stable than that obtained in batch reactors [21]. Therefore, high-gravity RPB reactors are promising candidates for the continuous production of high-quality QDs [22].…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Silver Sulfide Quantum Dots Via the Liquid–Liquid Interface Reaction in a Rotating Packed Bed Reactor

Liu

Zhao

et al. 2019

Trans. Tianjin Univ.

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We developed the high-gravity coupled liquid-liquid interface reaction technique on the basis of the rotating packed bed (RPB) reactor for the continuous and ultrafast synthesis of silver sulfide (Ag 2 S) quantum dots (QDs) with near-infrared (NIR) luminescence. The formation of Ag 2 S QDs occurs at the interface of microdroplets, and the average size of Ag 2 S QDs was 4.5 nm with a narrow size distribution. Ag 2 S QDs can disperse well in various organic solvents and exhibit NIR luminescence with a peak wavelength at 1270 nm under 980-nm laser excitation. The mechanism of the process intensification was revealed by both the computational fluid dynamics simulation and fluorescence imaging, and the mechanism is attributed to the small and uniform droplet formation in the RPB reactor. This study provides a novel approach for the continuous and ultrafast synthesis of NIR Ag 2 S QDs for potential scale-up.

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A facile method for preparation of emulsion using the high gravity technique

Cited by 10 publications

References 47 publications

Efficient Construction of pH-Stimuli-Responsive Colloidosomes with High Encapsulation Efficiency

Efficient Construction of pH-Stimuli-Responsive Colloidosomes with High Encapsulation Efficiency

High-gravity-assisted Fabrication of Self-assembled Colloidosomes

Synthesis of Silver Sulfide Quantum Dots Via the Liquid–Liquid Interface Reaction in a Rotating Packed Bed Reactor

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