A Facile Procedure for the Conversion of Oximes to Ketones and Aldehydes with Potassium Dichromate in Dimethylformamide under Homogeneous Conditions

Abstract

Oxidative cleavage of oximes to their parent corresponding carbonyl compounds using potassium dichromate-dimethylformamide system under homogeneous conditions in good yields is described. The main advantage of the present method is no need of preparation of hexavalent chromium-based reagents due to using a polar aprotic solvent.

9-Anthraldehyde oxime: a synthetic tool for variable applications

“…From the topic of the present review, the anthraldehyde oxime 2 is easily converted into the corresponding aldehyde 4 under oxidative conditions by using the cetyltrimethylammonium permanganate (CTAP) as an oxidizing agent in DCM as solvent at 25 °C (Scheme 27). The reaction is fast (15 min) and affords the desired aldehyde in excellent yields (96%) and high purity of the final product [69].…”