2018
DOI: 10.1002/jhet.3164
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A Facile Synthesis of Xanthene‐1,8(2H)‐dione Derivatives by Using Tetrapropylammonium Bromide as Catalyst

Abstract: Several new derivatives of 9‐aroyl‐3,4,5,6,7,9‐hexahydro‐1H‐xanthene‐1,8(2H)‐dione have been synthesized in yields varying from high to excellent by the condensation reaction of arylglyoxals with 1,3‐diketones (cyclohexane‐1,3‐dione or dimedone) and TPAB as an inexpensive, recoverable, and non‐toxic catalyst in the presence of ethanol/water under reflux conditions.

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Cited by 20 publications
(9 citation statements)
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“…In continuation of our efforts on synthesis of new heterocyclic compounds by using MCRs [37][38][39][40][41][42][43][44][45][46][47], herein we report the efficient synthesis of 5-(2-hydroxy-4-oxoquinolin-3(4H)-ylidene)-6-aryl-5,6-dihydroimidazo [2,1-b] [1,3,4] thiadiazol-7-ium hydroxides 4a-k by a one-pot three-component reaction (TCR) of aryl glyoxal monohydrates 1a-k, quinoline-2,4-diol 2 and 5-ethyl-1,3,4-thiadiazol-2-amine 3 in water under reflux conditions. The synthesized new compounds are interesting from the biological and pharmaceutical points of view (Scheme 1).…”
Section: Resultsmentioning
confidence: 99%
“…In continuation of our efforts on synthesis of new heterocyclic compounds by using MCRs [37][38][39][40][41][42][43][44][45][46][47], herein we report the efficient synthesis of 5-(2-hydroxy-4-oxoquinolin-3(4H)-ylidene)-6-aryl-5,6-dihydroimidazo [2,1-b] [1,3,4] thiadiazol-7-ium hydroxides 4a-k by a one-pot three-component reaction (TCR) of aryl glyoxal monohydrates 1a-k, quinoline-2,4-diol 2 and 5-ethyl-1,3,4-thiadiazol-2-amine 3 in water under reflux conditions. The synthesized new compounds are interesting from the biological and pharmaceutical points of view (Scheme 1).…”
Section: Resultsmentioning
confidence: 99%
“…In continuation of our research on the synthesis of novel heterocyclic compounds , herein, we report an efficient synthesis of benzo[ g ]thiazolo[2,3‐ b ]quinazolin‐4‐ium and benzo[ g ]benzo[4,5]thiazolo[2,3‐ b ]quinazolin‐14‐ium hydroxides by the one‐pot, three‐component reaction of aryl glyoxal monohydrates, 2‐hydroxy‐1,4‐naphthoquinone, and 2‐aminothiazole or 2‐aminobenzothiazole using TEA/ p ‐TSA as organocatalysts in H 2 O/acetone (2:1) at room temperature.…”
Section: Introductionmentioning
confidence: 99%
“…In continuation of our interest in the synthesis of new and various heterocyclic compounds , an efficient protocol for the synthesis of pyrano[3,2‐ c ]quinolines by multicomponent condensation of arylglyoxals, ethyl cyanoacetate, and 4‐hydroxyquinolin‐2(1 H )‐one in the presence of TPAB under reflux conditions was reported.…”
Section: Introductionmentioning
confidence: 99%