A Fairly Comprehensive Survey of Chronic Pain in Iranian Population: Prevalence, Risk Factors, and Impact on Daily Life

Mohammadzadeh, Fatemeh; Faghihzadeh, Soghrat; Lari, Mohsen Asadi; Mahdavi, Mohammad; Kheradmand, Jalil Arab; Noorbala, Ahmad Ali; Golmakani, Mohammad Mehdi; Mahrizi, Ali Asghar Haeri; Kordi, Ramin

doi:10.17795/jhealthscope-25467

Cited by 10 publications

(9 citation statements)

References 38 publications

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“…It was similar to, or even lesser than that reported among general population or other occupational groups (such as health care workers) in Iran. 3,25,26 This could, in principle, be due to one or more of the following reasons: (1) as previously described, the majority of these workers were young males seeking promotions in their first years on the job. Therefore, having a mean experience of <7 years, workers studied in our study expectedly had a lower mean age than those reported in populationbased studies.…”

Section: Discussionmentioning

confidence: 99%

“…While some studies have found a higher prevalence of chronic pain amongst women, 1,3 most studies have found no sex differences. 25,33 Defrin, et al, have discussed that the difference in response to pain is complex and may be affected by culture. 35 Similar to other published studies, 1,36 the most frequent marital status in workers with chronic pain was divorced/widowed.…”

Section: Discussionmentioning

confidence: 99%

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Prevalence and Predicting Factors of Chronic Pain among Workers of Petrochemical and Petroleum Refinery Plants

Shaygan

Yazdanpanah

2020

Int J Occup Environ Med

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Background: Taking into account the differences in job requirements and conditions, it is expected that workers in some occupations are more susceptible to pain than others. Objective: To examine the prevalence of chronic pain among workers of several petrochemical and petroleum refinery plants. We also examined the predictive role of psycho-familial variables (depression, work-family conflict and job stress) in causing chronic pain when controlling for demographic and occupational factors. Methods: This cross-sectional study was carried out among 674 workers. Those with chronic pain were identified by affirmative answers to screening questions based on the ICD-11 criteria. Results: There were 162 (24.0%; 95% CI 20.8% to 27.3%) workers meeting the ICD11 criteria for chronic pain. Headache was the most frequently reported pain (29.9%). We found a significantly (p=0.03) higher prevalence of pain among the middle age than in other age groups. Chronic pain more frequently affected divorced/widowed workers (p<0.001), and those with more work experience (p=0.04). Workers with chronic pain reported significantly higher levels of depression (p<0.001), job stress (p=0.007), and work-family conflict (p<0.001). After controlling for demographic and occupational factors, depression (p<0.001) and work-family conflict (p=0.003) were found to be independent predictors of chronic pain among studied workers. Conclusion: Workers who experience higher levels of depression, work-family conflict and job stress might be more prone to chronic pain. The majority of these factors are modifiable, and the problem may thus be solved by establishing appropriate screening programs, and availability of proper services and education.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Prevalence and Predicting Factors of Chronic Pain among Workers of Petrochemical and Petroleum Refinery Plants

Shaygan

Yazdanpanah

2020

Int J Occup Environ Med

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“…With increasing age, the work ability of workers in physically demanding jobs reduces more than the workers in mentally demanding jobs (7). Because the increase in the age leads to the chronic low back pain and knee pain in these people (24). As a result, the necessary measures should be taken to reform their tasks.…”

Section: (N = 15)mentioning

confidence: 99%

Work Ability of the Personnel of a Petrochemical Company and the Relationship Between Age and Physical Activities

2016

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Background: Given the importance of the fit between workers' physical and mental abilities and their job needs, it is of great importance to assess, maintain and promote the work ability of the people. Objective: The current study, conducted in a petrochemicals company, aimed to assess the work ability of the personnel and its relationship with age and physical demands of work. Methods: The current cross sectional descriptive analytical study was conducted on 208 employees working in a petrochemical company. The authors studied different occupational groups including operators, administrative, laboratory, maintenance and warehouse personnel. The required data were collected from the target groups using self-report work ability index questionnaire. To analyze the data, SPSS software version 21 was used. The analysis was conducted using t-test, ANOVA and Pearson correlation coefficient.

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“…This pain may directly and/or indirectly affect the structure and function of nerve cells [3,4]. The prevalence of Iranians suffering from neuropathic pain is calculated between 2%-40% of adults and is it is increasing over time [5]. About 20% (50 million) of the American population suffers from neuropathic pain, highlighting the importance of this disease [6].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Effect of (S)-3,4-Dicarboxyphenylglycine as a Metabotropic Glutamate Receptors Subtype 8 Agonist on Thermal Nociception Following Central Neuropathic Pain

Hosseini¹,

Parviz²,

Shabanzadeh³

et al. 2021

Asian Spine J

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In this study, we decided to change the activity of periaqueductal gray (PAG)'s metabotropic glutamate receptors subtype 8 (mGluR8) by means of its specific agonist, (S)-3,4-dicarboxyphenylglycine (DCPG), and by knock downing it with mGluR8 siRNA. We then evaluated the changes in animal pain threshold levels in the face of painful thermal stimuli (thermal hyperalgesia). Purpose: Although several mechanisms have been examined for central neuropathic pain, researchers have so far failed to find the precise mechanism for the development and progression of this type of pain. Hyperalgesia is one of the most important complications of central neuropathic pain and there is not a consensus among researchers about the exact cause of this complication. In this study, we investigated the effect of activation of the PAG region mGluR8 on the threshold of pain response to thermal noxious stimulus in rats and measured mGluR8 expression. Overview of Literature: Spinal cord injury (SCI) produces an decrease in mGluR2/3 expression in the injured and vehicle-treated groups compared to normal levels, APDC and L-AP4 treated groups had higher expression levels of mGluR2/3. These findings suggesting that the level of mGluR expression after SCI may modulate nociceptive responses. Methods: Male Wistar rats were randomly assigned to five groups (n=10 per group). The clip compression injury model was used to induce chronic central neuropathic pain. Three weeks after SCI, DCPG, siRNA, or normal saline were administered to the intra-ventrolateral PAG region. Withdrawal threshold to the noxious thermal stimulus (e.g., heat hyperalgesia) was assessed through the tail-flick test. In order to assure involvement of this receptor, pain responses were compared with mice that received GRM8 siRNA. Results: We found that the mGluR8 agonist DCPG increased lead to an increased expression of mGluR8 in the PAG region. We also found that SCI can decrease the threshold of response to painful thermal stimuli; however, activation of mGluR8 with DCPG agonist did not significantly improve the tail-flick response. Conclusions: The results revealed that activation of mGluR8 in PAG is not capable of improving the thermal hyperalgesia threshold. Based on the decreased expression of mGluR8 after SCI induced by clip compression injury and its significant increase after treatment of siRNA against mGluR8, this method might still hold promise as an effective treatment of neuropathic pain. It can be concluded that increased expression of mGluR8 is due to the fact that DCPG prevents the death of neurons that express these receptors.

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A Fairly Comprehensive Survey of Chronic Pain in Iranian Population: Prevalence, Risk Factors, and Impact on Daily Life

Cited by 10 publications

References 38 publications

Prevalence and Predicting Factors of Chronic Pain among Workers of Petrochemical and Petroleum Refinery Plants

Prevalence and Predicting Factors of Chronic Pain among Workers of Petrochemical and Petroleum Refinery Plants

Work Ability of the Personnel of a Petrochemical Company and the Relationship Between Age and Physical Activities

Evaluation of the Effect of (S)-3,4-Dicarboxyphenylglycine as a Metabotropic Glutamate Receptors Subtype 8 Agonist on Thermal Nociception Following Central Neuropathic Pain

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