A familial case series of valgus slipped capital femoral epiphysis

Assi, Chahine; Mansour, Jad; Samaha, Camille; Yammine, Kaissar

doi:10.1007/s00590-019-02472-w

Cited by 2 publications

(2 citation statements)

References 22 publications

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“…After filtering out duplicate, off-topic, and non-English articles, we retrieved a total of 27 papers with 32 SCFE patients older than 18 years. The literature search process is depicted in Figure 6, and detailed information on the retrieved cases is listed in Table 3 [4–30] . The age of the patients at the time of onset ranged from 19 to 79 years, with a mean of 29.7 years, and of the 32 patients, 23 were men and 9 were women.…”

Section: Resultsmentioning

confidence: 99%

“…In situ fixation NA No slippage of the contralateral hip Nourbakhsh et al [23] 2008 24 Female Bilateral Hypothyroidism No surgery NA NA Oommen et al [24] 2009 29 Male Bilateral Hashimoto thyroiditis In situ fixation with a screw 3 y Could walk unaided, radiographic fusion of both epiphyses Brady and Price [7] 2010 No evidence of slip in the contralateral hip Koteles and Lewi [19] 2010 19 Male Bilateral Hypothyroidism Open reduction and internal fixation 3 mo Laboratory results and radiology findings tended to be normal Hu et al [15] 2011 29 Male Left Cranio-pharyngioma In situ fixation with a pin 18 mo No osteonecrosis or contralateral SCF, closed bilateral proximal femoral epiphyses Marquez et al [20] 2014 28 Female Right Hypothyroidism In situ fixation with screws 12 mo No slip in the contralateral proximal femoral epiphysis Soleymanha et al [26] 2015 28 Female Left Cranio-pharyngioma In situ fixation with a screw 4 mo Full weight-bearing walk Song et al [27] 2015 [4] 2016 47 Female Left Inhaled corticosteroids THA NA NA Chan et al [9] 2018 24 Male Right Pituitary tumor Dunn procedure NA NA Gupta et al [13] 2018 23 Male Left Hypopituitarism NA NA NA Assi et al [6] 2019 56 Female Left NA No surgery NA NA Huang and Hsu [17] 2019 29 Male Left Hypogonadism Dunn procedure 6 mo Left hip mobility gradually improved, no slip in right hip Speirs et al [28] 2019 [30] 2019 27 Female Bilateral Gene mutation In situ fixation 7 mo Symptomatic relief Katzen et al [18] 2020 femoral anteversion could be specifically related to the development of SCFE. Paez et al [37] suggested that morphological changes in the acetabulum of SCFE patients may be related to the etiology of their condition.…”

Section: Etiology and Mechanismmentioning

confidence: 99%

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Slipped capital femoral epiphysis with hypopituitarism in adults

et al. 2021

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Rationale: Slipped capital femoral epiphysis (SCFE) is a common disease in pediatric orthopedics. Most research on SCFE has focused on high-risk groups or the whole population, and studies focusing on adult SCFE patients are rare. In the present study, we report the case of an adult patient with SCFE. Patient Concern: A 37-year-old man presented to our clinic with persistent pain that was poorly localized to both hips, groin regions, and thighs for more than 1 year. Diagnoses: A bilateral hip X-ray examination was performed, and the femoral epiphyses were found to be unfused on both sides. Low levels of growth hormone (GH), insulin-like growth factor-1 (IGF-1), triiodothyronine (T3), thyroxine (T4), follicle-stimulating hormone, luteinizing hormone, estradiol, and testosterone, and high levels of thyroid-stimulating hormone, prolactin, and cortisol. Interventions: Hormone-substitution therapies (levothyroxine sodium to treat hypothyroidism and testosterone enanthate to treat hypogonadism) were prescribed. Total hip arthroplasty was performed to treat femoral epiphysis slippage. Outcomes: After 6 months of postoperative follow-up, the patient's gait improved significantly, and bilateral hip pain was relieved. Lessons: When treating adults with SCFE, clinicians must be alert to endocrine disorders. Comprehensive imaging evaluation is crucial for the accurate diagnosis and selection of an appropriate treatment.

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Section: Resultsmentioning

confidence: 99%

Section: Etiology and Mechanismmentioning

confidence: 99%

Slipped capital femoral epiphysis with hypopituitarism in adults

et al. 2021

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Valgus slipped capital femoral epiphysis: a systematic review

Assi

Mansour

Kouyoumdjïan

et al. 2020

Journal of Pediatric Orthopaedics B

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Valgus slipped capital femoral epiphysis (SCFE) is a rare entity which leads to a proximolateral displacement of the hip epiphysis. The literature on valgus SCFE consists of case reports or case series. Since no evidence synthesis has been conducted, a systematic review on all published cases of valgus SCFE was conducted. The search strategy located 27 studies comprising 74 subjects with 96 hips. Demographic results were as follows: female/male ratio was of 1.65, and the mean age at presentation was 13.0 ± 2.54 years. Bilateral cases were recorded in 31.1%. Hip pain was the most frequent symptom followed by limping. The most frequent clinical sign was the limitation of medial internal rotation. Comorbidities were present in 65.6% of patients, mostly as endocrine or metabolic disorders. The mean neck-shaft angle was 149.2 ± 9.2°, the mean physis-shaft angle was 83.3 ± 9.7°, the neck-physis angle was 36.1 ± 21.5°, and the posterior physeal tilt angle was 23 ± 6.07°. The physeal tilt was lateral in 90% of cases. Treatment was based on screws in 70.8% of cases, a femoral osteotomy in 18.75%, and the remaining had a combination of surgical procedures. Two out of the three screw migrations occurred following fixation with more than one screw. All major complications (8.3%) had the potential of developing osteoarthritis in the future. Valgus SCFE entity demonstrates distinctive demographic, clinical and radiological results. This rare entity should be always included in the differential diagnosis of hip pain or limping in children.

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A familial case series of valgus slipped capital femoral epiphysis

Cited by 2 publications

References 22 publications

Slipped capital femoral epiphysis with hypopituitarism in adults

Slipped capital femoral epiphysis with hypopituitarism in adults

Valgus slipped capital femoral epiphysis: a systematic review

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