A family of oligo(p‐phenylenevinylene) derivative aggregation‐induced emission probes: Ultrasensitive, rapid, and anti‐interfering fluorescent sensing of perchlorate via precise alkyl chain length modulation

Abstract

The precise regulation of interactions provided by aggregation‐induced emission (AIE) probes is of considerable significance for improving the sensing performance in the field of on‐site detection. Here, a highly sensitive perchlorate detection probe was designed by precisely modulating the van der Waals interactions by adjusting the length of the alkyl chain. The optimized AIE probe demonstrated superior perchlorate detection performance owing to its strong van der Waals interactions with perchlorate, including a low detection limit (53.81 nM), rapid response (<5 s), and excellent specificity even in the presence of 16 interfering anions. In addition, a hydrogel‐based device loaded with the probe was constructed to achieve ultrasensitive recognition of perchlorate particles with a detection limit as low as 15 fg under a fluorescence microscope. Moreover, the practicality of the probe was further verified by employing a sensing chip in a portable detector, and thus the probe has been proven to be highly promising for trace perchlorate monitoring in real scenarios. We expect the present study to be of great value for the efficient design of high‐performance fluorescent probes.

Ultrasensitive Lateral Flow Immunoassay for Fumonisin B1 Detection Using Highly Luminescent Aggregation-Induced Emission Microbeads

“…The signal intensity of conventional fluorescent nanoparticles, which is highly influenced by the concentrations of loading fluorophores [ 21 ], is the core parameter for their sensitive utilization as reporters in LFIA [ 22 ]. However, the loading amounts of conventional fluorophores are limited because of their ACQ effect, resulting in limited signal intensity of fluorescent microbeads and the insufficient sensitivity of LFIA [ 23 , 24 , 25 ]. Hence, a novel type of fluorophores with aggregation-induced emission (AIE) effect, also called AIEgens, have attracted enormous attention in producing ultrabright nanoprobes [ 26 , 27 , 28 , 29 ].…”

Synergetic effect of pyrene-based fluorescent probes for trace nitroaniline sensing

“…However, these substituents can play a significant role to affect the molecular packing via tuning the intramolecular interactions, and this can result in excellent emission behaviour. 28,29 Herein, we have designed a set of pyrene-based molecules for nitroaniline detection, where two 2-hydroxypyrene units are connected by different alkyl (methyl or n-pentyl) or 1,4-ethylbenzene bridges; 30 the n-hexyl derivative was decorated at the 7-position to improve solubility. As expected, the three compounds display clear ''pyrene-like'' absorption, and the bridged unit exerts only a limited effect on the optical behaviour.…”

A rigid-flexible steric blocking strategy for highly bright and ultrawide piezochromism in the deep-red/near-infrared region

“…On the one hand, the flexible alkyl chain can hinder molecules from approaching each other in solid, reduce close p-p interactions, and increase the PLQY of the material. [33][34][35][36] The flexible portion can also provide a moderate free volume for molecular rearrangement during compression and decompression. On the other hand, rigid carbazole planes can increase the crystallization capability of the material since molecules containing simple long alkyl chains are usually difficult to crystallize.…”