A Feasibility Study of a New Unibody Branched Stent Graft Applied to Reconstruct the Canine Aortic Arch

Li, W.; Zhai, Shengli; Xu, Ke; Li, Q.; Zhong, Hongshan; Li, T.; Zhang, Z.

doi:10.1016/j.ejvs.2018.02.021

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…13 There are many reports about modular branched stent-graft and unibody branched stent-grafts. [10][11][12][14][15][16][17][18][19][20][21] In this study, we designed a new unibody outer-branched stent-graft system, which has many advantages. First, there was no bare stent at the proximal end of the main stent-graft.…”

Section: Discussionmentioning

confidence: 99%

Complete Endovascular Reconstruction of the Canine Ascending Aorta, Aortic Arch, and Supra-Aortic Vessels by Implanting a New Unibody Outer Double-Branched Stent-Graft

et al. 2022

J Endovasc Ther

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Purpose: We evaluated the feasibility and safety of using a new unibody outer double-branched stent-graft system to reconstruct the canine ascending aorta, aortic arch, and supra-aortic vessels. Materials and methods: The outer-branched stent-graft was a unibody design. The branched stent-graft consisted of a main stent-graft and 2 branches. The introducer system included a tri-channel catheter, 2 detachable sleeves, a front fixing device, a constraining wire, and a curved outer sheath. The branched stent-graft was loaded into the introducer system. Ten adult mongrel dogs underwent general anesthesia, and the branched stent-grafts were deployed into the canine ascending aorta, aortic arch, and supra-aortic vessels by the introducer system. All animals were followed up for 3 months. At the end of the follow-up period, computed tomographic angiography (CTA) was performed to observe the patency of the branched stent-grafts. Results: The mean operation time was 142.7±13.7 minutes. The mean fluoroscopy time was 20.73±2.22 minutes. The mean dosage of contrast agent was 95.9±8.7 mL. During the operation, the tri-channel catheters successfully paralleled the wires in the aorta. All 10 branched stent-grafts were successfully implanted into the canine ascending aorta and aortic arch. There were no symptoms of cerebral embolization and no incision infection during the follow-up period. Computed tomographic angiography and specimens showed that the branched stent-grafts and native vessels were patent, the inner surfaces of the branched stent-grafts were covered by neointima, and there was no retrograde aortic dissection in the ascending aorta. Conclusions: This animal research demonstrated that the unibody outer double-branched stent-graft system could be applied to reconstruct the canine ascending aorta, aortic arch, and supra-aortic vessels. Clinical Impact Thoracic endovascular aortic repair has been the main treatment method for aortic aneurysms or dissections involving the descending thoracic aorta. However, the aortic arch and ascending aorta remain the last segments of the aorta without a validated and routinely used endovascular option. In this research, we designed a new unibody outer branched stent-graft system to reconstruct the distal ascending aorta, aortic arch and supra-aortic vessels. The unibody outer branched stent-graft system could be applied to treat aortic pathologies which involve the middle and distal proximal ascending aorta, aortic arch and proximal descending aorta.

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Section: Discussionmentioning

confidence: 99%

Complete Endovascular Reconstruction of the Canine Ascending Aorta, Aortic Arch, and Supra-Aortic Vessels by Implanting a New Unibody Outer Double-Branched Stent-Graft

et al. 2022

J Endovasc Ther

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“…Further, the cost of EVAR appears lower than open surgery of aortic aneurysms (7,8). Technical developments of aortic stent grafts over the last decades have enabled EVAR to treat patients with complex aortic aneurysms such as the use of fenestrated and branched aortic stent grafts for preservation of renal and visceral arterial branches (6,(9)(10)(11), thus improving the durability and safety of the implanted endovascular stent grafts.…”

Section: Introductionmentioning

confidence: 99%

Synchrotron radiation computed tomography versus conventional computed tomography for assessment of four types of stent grafts used for endovascular treatment of thoracic and abdominal aortic aneurysms

Sun

Reis

2018

Quant. Imaging Med. Surg.

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“…In their paper, Li et al have presented a new device for treating thoracic aortic pathologies involving the arch, which has demonstrated promising results on a canine model in terms of feasibility and ease of deployment. 1 Aortic arch device development is currently a major research topic for innovative designs to meet the challenges of treatment in this area: mainly the risk of stroke and patient specific complex 3D anatomy. 2 The ideal device should feature conformability, simplicity of deployment, durability, low profile delivery system, and short-and longterm safety.…”

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confidence: 99%

Commentary on “A Feasibility Study of a New Unibody Branched Stent Graft Applied to Reconstruct the Canine Aortic Arch”

Schwein

Georg

Chakfé

2018

European Journal of Vascular and Endovascular Surgery

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A Feasibility Study of a New Unibody Branched Stent Graft Applied to Reconstruct the Canine Aortic Arch

Abstract: The unibody branched stent graft system could be used to reconstruct the aortic arch. The animal experimental procedures demonstrated the safety and feasibility of the unibody branched stent graft system.

Cited by 3 publications

References 19 publications

Complete Endovascular Reconstruction of the Canine Ascending Aorta, Aortic Arch, and Supra-Aortic Vessels by Implanting a New Unibody Outer Double-Branched Stent-Graft

Complete Endovascular Reconstruction of the Canine Ascending Aorta, Aortic Arch, and Supra-Aortic Vessels by Implanting a New Unibody Outer Double-Branched Stent-Graft

Synchrotron radiation computed tomography versus conventional computed tomography for assessment of four types of stent grafts used for endovascular treatment of thoracic and abdominal aortic aneurysms

Commentary on “A Feasibility Study of a New Unibody Branched Stent Graft Applied to Reconstruct the Canine Aortic Arch”

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