A female case of Fox-Fordyce disease

Roche, Hélène; Roche-Kubler, B.; Blanc, Dominique; Algros, M.-P.; Faivre, B.; Aubin, F.

doi:10.1684/ejd.2016.2752

Cited by 3 publications

(3 citation statements)

References 6 publications

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“…27 The fact that 16% of FFD cases reviewed in this article erupted after laser hair removal, a procedure that can cause damage to follicular infundibulum, also supports obstruction as a cause of FFD. 2,9,10,12,[28][29][30][31][32][33][34] Finally, hormonal changes also play a role in the pathophysiology of the disease.…”

Section: Calcipotriol and Betamethasonementioning

confidence: 99%

Pathophysiology, clinical findings, and management of Fox‐Fordyce disease: A systematic review

Salloum

Bouferraa

Bazzi

et al. 2021

J of Cosmetic Dermatology

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Background: Fox-Fordyce (FFD), also known as apocrine military, is an uncommon chronic inflammation of the apocrine sweat glands. It is characterized by pruritic, papular eruptions in apocrine-gland-bearing regions. FFD was described a century ago, but the exact pathogenesis of the disease and the management are not well understood. Aims:This paper provides a wide understanding of the pathophysiology, clinical findings, and management of Fox-Fordyce disease. Its aim is to help the physician to diagnose and manage this entity accordingly.Methods: A research was done using PubMed database on 12 April 12, 2020, and in order to retrieve all case reports, case series, cohort studies, randomized, and nonrandomized clinical trials were included describing FFD among patients.Results: A total of 43 articles and 68 patients were included in the study. The majority of patients were young females. The disease was bilateral in 90%, affected the axillae and to a lesser extent the pubic and the periareolar areas and rarely the thoracic area, the abdominal area, and the face. FFD followed a relapsing and remitting course, and an evident improvement in disease course was noted after menopause. Conclusion:The typical FFD patient is a post-pubertal female and pre-menopause, presenting with pruritic papules in apocrine-gland-bearing regions. FFD can be sporadic or occurs in family, and it can be asymptomatic in 1/(3-4) of patients and can be triggered by laser hair removal and hormonal changes. Further randomized clinical trials assessing different treatment of FFD are now warranted.

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Section: Calcipotriol and Betamethasonementioning

confidence: 99%

Pathophysiology, clinical findings, and management of Fox‐Fordyce disease: A systematic review

Salloum

Bouferraa

Bazzi

et al. 2021

J of Cosmetic Dermatology

View full text Add to dashboard Cite

show abstract

“…Fox-Fordyce Disease (FFD), also known as apocrine miliaria, is an inflammatory skin condition postulated to occur when apocrine or apo-eccrine sweat ducts become occluded and inflamed (20)(21)(22). FFD presents as flesh-colored to reddish-brown pruritic domeshaped papules in apocrine gland-bearing regions such as the axillae, groin, areolae, and inframammary folds ( Fig.…”

Section: Fox-fordyce Diseasementioning

confidence: 99%

“…FFD presents as flesh-colored to reddish-brown pruritic domeshaped papules in apocrine gland-bearing regions such as the axillae, groin, areolae, and inframammary folds ( Fig. 6) (21,(23)(24)(25). FFD affects women predominantly of child-bearing age and tends to resolve after menopause (24,26).…”

Section: Fox-fordyce Diseasementioning

confidence: 99%