A Female Monozygotic Twin Pair Discordant for Transsexualism

Garden, Gill; Rothery, D. J.

doi:10.1192/bjp.161.6.852

Cited by 18 publications

(15 citation statements)

References 12 publications

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“…There are also reports of MZ twin pairs discordant for GID in childhood (Garden & Rothery, 1992;Green & Stoller, 1971). Green (2000) reported 10 sets of transsexuals in the same family.…”

Section: Introductionmentioning

confidence: 94%

Gender identity disorder and anorexia nervosa in male monozygotic twins

Hepp

Milos

Braun-Scharm

2004

Intl J Eating Disorders

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“…There are also reports of MZ twin pairs discordant for GID in childhood (Garden & Rothery, 1992;Green & Stoller, 1971). Green (2000) reported 10 sets of transsexuals in the same family.…”

Section: Introductionmentioning

confidence: 94%

Gender identity disorder and anorexia nervosa in male monozygotic twins

Hepp

Milos

Braun-Scharm

2004

Intl J Eating Disorders

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“…In MF transsexualism, there are reports of six monozygotic (MZ) twin pairs concordant for transsexualism (Anchersen, 1956;Gooren, Frantz, Eriksson, & Rao, 1989;Green, 2000;Hyde & Kenna, 1977;Tsur, Borenstein, & Seidman, 1991;Zucker & Bradley, 1995), five MZ twin pairs discordant for transsexualism (Gooren et al, 1989;Green & Stoller, 1971;Hepp, Milos, & Braun-Sharm, 2004;Zucker & Bradley, 1995), and one report of two dizygotic (DZ) transsexual male triplets with a nontranssexual female co-triplet (McKee, Roback, & Hollender, 1976). In FM transsexual twins, one concordant (Sadeghi & Fakhrai, 2000) and four discordant MZ pairs (Garden & Rothery, 1992;Green & Stoller, 1971;Segal, 2006) have been reported. Moreover, most of the MZ and DZ twin case reports share not only genes but also many environmental factors.…”

Section: Introductionmentioning

confidence: 95%

Familiality of Gender Identity Disorder in Non-Twin Siblings

et al. 2009

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Familial studies and reports of co-occurrence of gender identity disorder (GID) within a family may help to clarify the question of whether transsexualism is a familial phenomenon. In a sample of 995 consecutive transsexual probands (677 male-to-female [MF] and 318 female-to-male [FM]), we report 12 pairs of transsexual non-twin siblings (nine pairs of MF siblings, two pairs of MF-FM siblings, and one pair of FM siblings). The present study doubles the number of case reports of co-occurrence of transsexualism in non-twin siblings available in the literature. According to our data, the probability that a sibling of a transsexual will also be transsexual was 4.48 times higher for siblings of MF than for siblings of FM transsexual probands, and 3.88 times higher for the brothers than for the sisters of transsexual probands. Moreover, the prevalence of transsexualism in siblings of transsexuals (1/211 siblings) was much higher than the range expected according to the prevalence data of transsexualism in Spain. The study suggests that siblings of transsexuals may have a higher risk of being transsexual than the general population, and that the risk is higher for brothers than sisters of transsexuals, and for siblings of MF than FM transsexuals. Nevertheless, the risk is low.

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“…Only five pairs represent FTM MZ twins. Four pairs were discordant (Garden & Rothery, 1992;Green & Stoller, 1971;Segal, 2006) and only one was concordant for transsexualism (Sadeghi & Fakhrai, 2000). Seven additional MZ FTM transsexual twin pairs (two concordant and five discordant) were reported by Diamond and Hawk (2004).…”

mentioning

confidence: 83%

“…Several MZ twin pairs and one triplet (FTM and MTF) concordant or discordant for transsexualism have been reported (Anchersen, 1956;Buhrich, Bailey, & Martin, 1991;Garden & Rothery, 1992;Green, 2000;Green & Stoller, 1971;Hyde & Kenna, 1977;McKee, Roback, & Hollander, 1976;Sadeghi & Fakhrai, 2000;Segal, 2006;Zucker & Bradley, 1995). Only five pairs represent FTM MZ twins.…”

mentioning

confidence: 94%