A Fixed Stricture on Routine Cross-sectional Imaging Predicts Disease-Related Complications and Adverse Outcomes in Patients with Crohnʼs Disease

Chaudhry, Naueen A.; Riverso, Michael; Grajo, Joseph R.; Moser, Patricia; Zou, Fei; Homsi, Maher; Punglia, Darashana

doi:10.1097/mib.0000000000001054

Cited by 14 publications

(6 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In our study, we found that stenosis was 25 cases, of which 24 cases were active, mesenteric hypervascularity (comb sign) was 32 cases, of which 28 cases were active, and 8 cases showed mesenteric enlarged lymph nodes, which were active. Several studies have reported that stenosis was related to the activity of the lesion [ 4 , 12 ]. Chaudhry et al [ 12 ] found that stenosis and the other complications, such as fistula and abscess, were reciprocal causation and affected the prognosis.…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have reported that stenosis was related to the activity of the lesion [ 4 , 12 ]. Chaudhry et al [ 12 ] found that stenosis and the other complications, such as fistula and abscess, were reciprocal causation and affected the prognosis. Sakurai et al [ 13 ] reported that comb sign and mesenteric enlarged lymph nodes were important predictors of mucosal ulceration; It is worth noting that the size of the ulcer and affected area is the most important part of the CD endoscopy score.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Computed Tomography Enterography: Quantitative Evaluation on Crohn’s Disease Activity

Cheng

Xie

Yang

et al. 2018

Gastroenterology Research and Practice

View full text Add to dashboard Cite

Objective To explore the feasibility of computed tomography enterography (CTE) in the quantitative evaluation of the activity of Crohn's disease (CD). Methods There were 49 CD patients with whole clinical, enteroscopy, and CTE data to be analyzed retrospectively. The patients were graded as inactive (0–2), mild (3–6), and moderate-severe group (>6) based on simplified endoscopic activity score for Crohn's disease (SES-CD). The differences in bowel wall thickening, mural hyperenhancement in the portal vein period, and the ΔCT values were analyzed among groups using ANOVA (analysis of variance) and q test. Then, the parameters were correlated with SES-CD, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR). Results In the 49 patients, 13 ones were inactive, 19 ones were mild, and 17 ones were moderate-severe; the thickness of bowel wall, mural hyperenhancement in the portal vein period, and ΔCT value among groups were all significantly different (P < 0.001 in all). Correlative analysis showed that compared with the SES-CD, the bowel wall thickening (r = 0.564, P < 0.001), mural hyperenhancement in the portal vein period (r = 0.585, P < 0.001), and ΔCT value (r = 0.533, P < 0.001) were moderately correlated. Conclusion The mural hyperenhancement in the portal vein period, bowel wall thickening, and ΔCT value can accurately and quantitatively assess the activity of CD lesions and are potential visual biomarkers of CD lesions.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Computed Tomography Enterography: Quantitative Evaluation on Crohn’s Disease Activity

Cheng

Xie

Yang

et al. 2018

Gastroenterology Research and Practice

View full text Add to dashboard Cite

show abstract

“…In the case of a proximal (upstream) stenosis with obstructive properties and a distal collapsed bowel (downstream), further aboral stenosis (tandem stenoses) can be masked. The diagnostic requirement of a prestenotic dilation may thus reduce the sensitivity for the detection of stenosis [44][45][46][47][48]. Stenoses suspected on MRE without verified prestenotic dilation should therefore be described as "probable stenosis".…”

Section: Recommendationmentioning

confidence: 99%

Intestinal MRI in Inflammatory Bowel Disease – Literature and Survey-Based Recommendations regarding Reporting by the German Radiological Society (DRG) and the German Competence Network for Inflammatory Bowel Diseases

Weßling

Kucharzik

Bettenworth³

et al. 2023

Rofo

View full text Add to dashboard Cite

Background MR-enterography/enteroclysis (MRE) is increasingly used for primary diagnosis, detection of complications, and monitoring of patients with inflammatory bowel disease (IBD). Standardization of reporting is relevant to ensure quality of the methodology and to improve communication between different faculties. The current manuscript describes the features that are required for optimized reporting of MRE in IBD. Methods An expert consensus panel of radiologists and gastroenterologists conducted a systematic search of the literature. In a Delphi process, members of the German Radiological Society (DRG) and members of the Competence Network for Inflammatory Bowel Diseases voted on relevant criteria for the reporting of findings in MRE. Based on the voting results, statements were developed by the expert consensus panel. Results Clinically relevant aspects of MRE findings have been defined to optimize reporting and to standardize terminology. Minimal requirements for standardized reporting are suggested. The statements focus on the description of disease activity as well as on complications of IBD. Attributes of intestinal inflammation are described and illustrated by exemplary images. Conclusion The current manuscript provides standardized parameters and gives practical recommendations on how to report and how to characterize MRE findings in patients with IBD. Key points: Citation Format

show abstract

“…Die aktuell gängige Definition beschreibt eine Einengung des Lumens mit einer prästenotischen Dilatation > 25 mm des vorgeschalteten Darmsegments [16,54,55]. Die Forderung nach einer prästenotischen Dilatation reduziert möglicherweise die Sensitivität für die Detektion von Stenosen [56,57,58,59,60]. Der Vorteil der Darmsonografie liegt darin, dass die Motilität des vorgeschalteten Darmsegmentes zur Identifizierung der Stenose als Kriterium mit herangezogen werden kann.…”

Section: Stenosierender Morbus Crohnunclassified

Positionspapier zur Befunderhebung von Darmultraschallbefunden bei chronisch entzündlichen Darmerkrankungen

et al. 2022

View full text Add to dashboard Cite

Zusammenfassung Hintergrund Zur Diagnosestellung, Erkennung von Erkrankungskomplikationen sowie zur Verlaufskontrolle bei Patienten mit Morbus Crohn und Colitis ulcerosa wird zunehmend der Darmultraschall eingesetzt. Eine systematische Befunderhebung und Dokumentation sind wichtig, um die Qualität der Befunderstellung und die Kommunikation zwischen den Fachgruppen zu verbessern. Das vorliegende Positionspapier beschreibt die Voraussetzungen für eine optimale Befunderhebung des Darmultraschalls bei Patienten mit chronisch-entzündlichen Darmerkrankungen (CED). Methoden Eine Experten-Konsensusgruppe bestehend aus Gastroenterologen, Radiologen, Pathologen, Kinder- und Jugend-Gastroenterologen und Chirurgen führte eine systematische Literaturrecherche durch. In einem Delphi-Verfahren wurde unter Mitgliedern des Kompetenznetzes Darmerkrankungen und der Deutschen Röntgengesellschaft (DRG) über relevante Kriterien bei der Befunderhebung von Darmultraschallbefunden abgestimmt. Die daraus resultierenden Statements wurden in einer Experten-Konsensusgruppe verabschiedet. Ergebnis Praxisorientierte Empfehlungen für eine optimale Befunderhebung mit einer standardisierten Terminologie wurden entwickelt. Der Fokus der Erhebung lag auf der Beschreibung der Entzündungsaktivität sowie der Komplikationen bei CED. Minimale Anforderungen für eine standardisierte Befunderhebung wurden definiert. Zusammenfassung Das vorliegende Manuskript bietet praktische Empfehlungen zur Optimierung und Vereinheitlichung der Befunderhebung bei Darmultraschall-Untersuchungen bei CED.

show abstract

A Fixed Stricture on Routine Cross-sectional Imaging Predicts Disease-Related Complications and Adverse Outcomes in Patients with Crohnʼs Disease

Abstract: Information from radiologic studies, especially the presence of fixed strictures, can predict future CD complications. These findings, along with smoking and ongoing inflammation, should alert the clinician to the possibility of future complications.

Cited by 14 publications

References 29 publications

Computed Tomography Enterography: Quantitative Evaluation on Crohn’s Disease Activity

Computed Tomography Enterography: Quantitative Evaluation on Crohn’s Disease Activity

Intestinal MRI in Inflammatory Bowel Disease – Literature and Survey-Based Recommendations regarding Reporting by the German Radiological Society (DRG) and the German Competence Network for Inflammatory Bowel Diseases

Positionspapier zur Befunderhebung von Darmultraschallbefunden bei chronisch entzündlichen Darmerkrankungen

Contact Info

Product

Resources

About