A flexible and bright surface-enhanced electrochemiluminescence film constructed from efficient aggregation-induced emission luminogens for biomolecular sensing

Li, Zihua; Zhou, Yusheng; Cui, Yuhan; Liang, Guodong

doi:10.1039/d2tb00400c

Cited by 3 publications

(1 citation statement)

References 59 publications

(62 reference statements)

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“…A62 was reported to have the lowest LOD so far of 3.16 × 10 −16 M, suggesting that Au NPs coated with flexile films are useful for ultra-low sensing. 137 The last chemosensor, A63 is a three component conjugated D–A polymer with the highest ECL emission due to the increase of AIE TPE moiety and weakened ICT effect from the organoboron moiety. A63 can detect both DA as well as epinephrine via quenching of the polymer dots with a LOD of 7 and 3 nM, respectively.…”

Section: Sensing Of Biomoleculesmentioning

confidence: 99%

Recent advances in aggregation-induced emission (AIE)-based chemosensors for the detection of organic small molecules

Chua,

Hui,

Chin

et al. 2023

Mater. Chem. Front.

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Section: Sensing Of Biomoleculesmentioning

confidence: 99%

Recent advances in aggregation-induced emission (AIE)-based chemosensors for the detection of organic small molecules

Chua,

Hui,

Chin

et al. 2023

Mater. Chem. Front.

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An “off-on-enhanced on” electrochemiluminescence biosensor based on resonance energy transfer and surface plasmon coupled 3D DNA walker for ultra-sensitive detection of microRNA-21

Li,

Zhong,

Zhang

et al. 2024

Analytica Chimica Acta

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Dual Gold Nanostructures-Based Stretchable Electrochemiluminescence Sensors for Hydrogen Peroxide Monitoring in Endothelial Mechanotransduction

Liu,

Wang,

Cheng

et al. 2024

ACS Sens.

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Hydrogen peroxide (H 2 O 2 ) release during blood flow is commonly provoked by the cyclic stretch and dynamic shear stress of endothelial cells and is of vital significance for maintaining vascular function. Flexible and stretchable electrochemical sensors show great capability in retrieving mechanical stimulation-induced H 2 O 2 variation; however, cell secretions, especially electroactive constituents' interferences, remain a big concern for sensing accuracy. Herein, we developed a stretchable electrochemiluminescence (ECL) sensor by synthesizing L012-reduced gold nanospheres and decorating them onto a polydimethylsiloxane film-supported gold nanotubes substrate (Au NTs/PDMS) to form dual gold nanostructure-modified meshwork interface. Given the specific reaction between L012 and H 2 O 2 , the as-prepared Au-L012/Au NTs/PDMS exhibited outstanding selectivity toward H 2 O 2 quantification. Through culturing human umbilical vein endothelial cells (HUVECs), real-time monitoring of transient H 2 O 2 release from mechanically sensitive HUVECs in stretching states was realized. This work successfully incorporated the ECL sensing model into in situ cellular sensing, therefore expanding the application mode of the ECL approach for health care and biomedical investigation.

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A flexible and bright surface-enhanced electrochemiluminescence film constructed from efficient aggregation-induced emission luminogens for biomolecular sensing

Abstract: Bright surface-enhanced electrochemiluminescence film (SEEF) was fabricated from an organic luminogen with aggregation-induced emission (AIEgen) feature on flexible substrates. Flexible carbonous substrates including carbon fiber cloth (GCFC) and carbon fiber...

Cited by 3 publications

References 59 publications

Recent advances in aggregation-induced emission (AIE)-based chemosensors for the detection of organic small molecules

Recent advances in aggregation-induced emission (AIE)-based chemosensors for the detection of organic small molecules

An “off-on-enhanced on” electrochemiluminescence biosensor based on resonance energy transfer and surface plasmon coupled 3D DNA walker for ultra-sensitive detection of microRNA-21

Dual Gold Nanostructures-Based Stretchable Electrochemiluminescence Sensors for Hydrogen Peroxide Monitoring in Endothelial Mechanotransduction

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