The Serenity-S1 is a production-optimised Advanced Telecommunications Computing
Architecture (ATCA) processing blade based on the AMD Xilinx Virtex Ultrascale+ device. It
incorporates many developments from the Serenity-A and Serenity-Z prototype cards and, where
possible, adopts solutions being used across CERN. Due to the shortage of components during the
recent semiconductor crisis, commonly used components in the prototypes had to be replaced by new
ones after qualification. In this work, we discuss various improvements to simplify
manufacturing, the performance of new components, some of the more difficult aspects of
procurement, the performance of production-grade Samtec 25 Gb/s optical firefly parts, and
concerns regarding the rack cooling infrastructure.