A flexible micromachined electrode array for a cochlear prosthesis

Nanoscale neuro-integrative coatings for neural implants

“…The potential of neural implants is clear from the prosthetic cochlear implant, a commonly used treatment for deafness that involves implanting electrode arrays into the cochlear region of the brain [1]. Other neural implants in various stages of development include micromachined neural prosthetic devices, which facilitate the functional stimulation of and recording from the central and peripheral nervous system [2][3][4][5].…”

Determination of the curling behavior of a preformed cochlear implant electrode array

“…Therefore, the development of more automated fabrication processes for the manufacturing of electrodes seems to be obligatory to reduce the variations in their bending behavior to improve residual hearing preservation results using preformed, perimodiolar electrode carriers. For example fabrication technologies known from micro-manufacturing, like thin film technologies, allow a higher degree of automation and have already been investigated in the context of neuroprosthesis [53][54][55][56].…”

Automatic spike detection based on adaptive template matching for extracellular neural recordings

“…Recent studies have applied one-and two-dimensional microelectrode arrays (MEAs), microwire arrays, and silicon substrate arrays that generally have higher levels of background noise and do not permit microelectrodes to be positioned to isolate the activity of single neurons (Potter et al, 2005;Hasegawa et al, 2004;Branner and Normann, 2000;Bell et al, 1998;DellaSantina et al, 1997;Zhelyaskov et al, 1995). Because these recordings are obtained from many sites, it is also impractical for investigators to manually tune spike detection algorithms and select thresholds to achieve acceptable performance from their spike detectors.…”