A Flexible Portable Glucose Sensor Based on Hierarchical Arrays of Au@Cu(OH)2 Nanograss

Abstract

Flexible physiological medical devices have gradually spread to the lives of people, especially the elderly. Here, a flexible integrated sensor based on Au nanoparticle modified copper hydroxide nanograss arrays on flexible carbon fiber cloth (Au@Cu(OH)2/CFC) is fabricated by a facile electrochemical method. The sensor possesses ultrahigh sensitivity of 7.35 mA mM−1 cm−2 in the linear concentration range of 0.10 to 3.30 mM and an ultralow detection limit down to 26.97 nM. The fantastic sensing properties can be ascribed to the collective effect of the superior electrochemical catalytic activity of nanograss arrays with dramatically enhanced electrochemically active surface area as well as mass transfer ability when modified with Au and intimate contact between the active material (Au@Cu(OH)2) and current collector (CFC), concurrently supplying good conductivity for electron/ion transport during glucose biosensing. Furthermore, the device also exhibits excellent anti-interference and stability for glucose detection. Owing to the distinguished performances, the novel sensor shows extreme reliability for practical glucose testing in human serum and juice samples. Significantly, these unique properties and the soft structure of silk fabric can provide a promising structure design for a flexible micro-device and a great potential material candidate of electrochemical glucose sensor.

2-dimensional nanoleaf-like porous copper nitrate hydroxide as an effective heterogeneous catalyst for selective oxidation of hydroxymethylfurfural to diformylfuran

“…Furthermore, the Cu2p core-level spectrum is then displayed in Fig. 3(a), and the peaks at 933.3 and 952.3 eV could be attributed to Cu 2+ [35], which was consistent to the valence state of Cu species in Cu2(OH)3NO3. On the other hand, the O1s core-level spectrum of LPCNH was deconvoluted into two underlying peaks (Fig.…”

Recent Advances in Materials for Enzyme-free Electrochemical Glucose Sensors

“…Copper (Cu) is also a popular catalytic material for glucose detection because of its low cost, nontoxicity, and high electrochemical activity. Identical to Ni-based materials, Cu-based materials, such as Cu, (39)(40)(41)(42)(43)(44)(45) CuO, (46)(47)(48)(49)(50) Cu 2 O, (51)(52)(53)(54) Cu(OH) 2 , (55) CuS, (56,57) and others, can be used for the electrocatalysis of glucose. Cu-based materials participate in the oxidation of glucose oxidation in various forms, such as nanocubes, nanorods, nanowires, nanosheets, and nanoflowers.…”

“…(103) Jiang et al fabricated a flexible sensor based on Au nanoparticle-modified copper hydroxide nanograss arrays on flexible carbon fiber cloth (Au@Cu(OH) 2 /CFC). (55) The excellent sensing properties were attributed to the collective effect of the superior electrochemical catalytic activity of Cu(OH) 2 nanograss arrays with a markedly increased electrochemically active surface area as well as the mass transfer ability of Au. Yang et al designed composite catalysts with Cu, Ni, and their oxides for the detection of glucose.…”

Wearable Noninvasive Glucose Sensor Based on CuxO NFs/Cu NPs Nanocomposites

“…Due to their stability and superior detection capability, several metal materials, especially gold [ 1 , 6 , 7 , 8 ], platinum [ 9 ], copper [ 10 , 11 ] and nickel [ 12 , 13 , 14 ], have gained a lot of emphasis in non-enzymatic glucose sensors [ 15 ]. Noble metal materials are pricey, which has hindered their utilization in non-enzymatic glucose sensors [ 16 ].…”