A fluorescein-based chemosensor for “turn-on” detection of Hg²⁺ and the resultant complex as a fluorescent sensor for S²⁻ in semi-aqueous medium with cell-imaging application: experimental and computational studies

Abstract

A fluorescein hydrazone based probe selectively recognizes Hg2+ ion with live cell imaging application.

Pyridine-Dicarbohydrazone-Based Polyacrylate Hydrogels with Strong Mechanical Property, Tunable/Force-Induced Fluorescence, and Thermal/pH Stimuli Responsiveness

“…Additionally, the result of fluorescence emission spectra in Figure c shows that the emission wavelength of the As-prepared hydrogel excited at 330 nm has red shifted from 515 to 646 nm, following the addition of Eu 3+ , with the color visually converting from blue to red under exposure to 365 nm UV light. According to previous research studies, the (pyridine-dicarbohydrazone)-based organic group contributed to the original blue fluorescence. − This phenomenon further demonstrates the existence of coordination between Eu 3+ and the (pyridine-dicarbohydrazone)-based cross-linker.…”

BODIPY Immobilized MCM‐41 Based Multianalyte Sensor: Application in Detection and Removal of Trivalent (Al3+, Cr3+) and Divalent (Cu2+, Hg2+) Metal Ions in Aqueous Media

“…The structural confirmation for the formation of (L) and (4) were provided by 1 H, 13 C NMR, FTIR and ESI-MS (Figure S3-S10). In the solution-state 1 H NMR spectra of non-silylated p-phenyl-Scheme 1.…”

“…[92] In the case of Al 3 + and Cr 3 + metal ions, no shifting in the position of carbonyl oxygen was seen. 1 H and 13 C NMR results show that the trivalent metal ions (Al 3 + , Cr 3 + ) bind with the À NH proton of p-aminobenzoic acid group after deprotonation, and the divalent metal ions (Cu 2 + , Hg 2 + ) interact with the carboxylic acid (À COOH) functionality. The 1 H NMR analysis shows no involvement of the phenolic group (À OH) with the metal ions.…”

“…Various human activities, such as coal combustion, mining operations, waste incineration, battery manufacturing, and other similar activities, as well as volcanic eruptions, produce mercury to the environment. [13,14] Among the different chemical states of mercury, the inorganic mercury is most prevalent hazardous, which can cause severe kidney and lung damage. [15,16] Hg 2 + ions are extensively diffused in aqueous media, and as a result, consuming fish and drinking water that contains high levels of mercury can result in serious health consequences.…”

Colorimetric and fluorometric probes for the optical detection of environmental Hg(ii) and As(iii) ions

“…Another fluorescein derived chemosensor 19 has been reported for the detection of Hg 2+ . The sensor 19 [70] is a fluorescein hydrazide coupled 2-(pyridine-2-ylmethoxy)-naphthalene-1-carbaldehyde moiety which exhibited excellent selectivity and sensitivity towards Hg Excited-state intramolecular proton transfer (ESIPT) active molecules are advantageous due to their excellent photostability, large stokes shift, and unique emission properties. Naphthalene derives sensor 20 [71] is an ESIPT active probe that has been able to detect Hg 2+ in CH 3 CNwater (9:1, v/v, pH=7.0, HEPES buffer) medium in a fluorescence ON to OFF fashion accompanied by a drastic change of color from colorless to yellow.…”