A fluorescent aptasensor for highly sensitive and selective detection of carcinoembryonic antigen based on upconversion nanoparticles and WS₂ nanosheets

Abstract

A highly sensitive fluorescent aptasensor for carcinoembryonic antigen (CEA) was developed by employing upconversion nanoparticles (UCNPs) as an energy donor and WS2 nanosheet as an energy acceptor, respectively. The polyacrylic...

A lateral flow strip for on-site detection of homocysteine based on a truncated aptamer

“…Through adaptive folding, aptamers develop unique secondary and tertiary structures, enabling them to specifically identify a wide range of targets such as small molecules, metal ions, toxins, proteins, and entire cells. 21–25 Truncation of aptamers is a conventional post-SELEX process, which can not only help understand the binding mechanism between targets and aptamers, but also improve the performance of aptamers. After truncation, the secondary structures of aptamers become more predictable and stable due to the shorter length of truncated aptamers.…”