A fluorescent sensor array based on antibiotic-stabilized metal nanoclusters for the multiplex detection of bacteria

Mousavizadegan, Maryam; Hosseini, Morteza; Sheikholeslami, Mahsa N.; Ganjali, Mohammad Reza

doi:10.1007/s00604-024-06374-5

Microchim Acta

2024

DOI: 10.1007/s00604-024-06374-5

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A fluorescent sensor array based on antibiotic-stabilized metal nanoclusters for the multiplex detection of bacteria

Maryam Mousavizadegan,

Morteza Hosseini,

Mahsa N. Sheikholeslami

et al.

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Cited by 4 publications

References 35 publications

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Enhanced Antibacterial Effect of Kanamycin‐Stabilized Nanoclusters

Rezapour,

Mousavizadegan,

Mortazavi

et al. 2024

ChemistrySelect

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Pertaining to the imminent problem of antibiotics resistance, and in turn the urgent need for new antibiotics, it is vital to generate new compounds that are effective against resistant species. For this, we have aimed to develop enhanced antibacterial compounds by merging antibiotics with nanomaterials to strengthen their activity. Hence, kanamycin‐stabilized gold, silver, and copper nanoclusters (NCs) were synthesized and investigated for their antibacterial activity. It was seen that the gold and silver NCs had increased antibacterial activity, especially against Escherichia coli, with an average decrease in the MIC for 4:1 for the silver and 2:1 for the gold NCs. The antibacterial activity against Staphylococcus aureus and Salmonella typhimurium was also increased, more significantly for the silver NCs. However, for the copper NCs, enhanced activity was not witnessed. Thus, it can be concluded that incorporating nanoclusters, especially gold and silver, with antibiotic ligands can enhance their antimicrobial activity.

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Enhanced Antibacterial Effect of Kanamycin‐Stabilized Nanoclusters

Rezapour,

Mousavizadegan,

Mortazavi

et al. 2024

ChemistrySelect

View full text Add to dashboard Cite

show abstract

Gold nanorod etching for sensitive aptamer-mediated colorimetric detection of Escherichia coli in water

Namjoo,

Shalileh,

Golbashy

et al. 2025

Microchemical Journal

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Machine learning-assisted image-based optical devices for health monitoring and food safety

Mousavizadegan,

Shalileh,

Mostajabodavati

et al. 2024

TrAC Trends in Analytical Chemistry

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A fluorescent sensor array based on antibiotic-stabilized metal nanoclusters for the multiplex detection of bacteria

Cited by 4 publications

References 35 publications

Enhanced Antibacterial Effect of Kanamycin‐Stabilized Nanoclusters

Enhanced Antibacterial Effect of Kanamycin‐Stabilized Nanoclusters

Gold nanorod etching for sensitive aptamer-mediated colorimetric detection of Escherichia coli in water

Machine learning-assisted image-based optical devices for health monitoring and food safety

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