A follow-up study of metabolic syndrome in schizophrenia

Yoca, Gökhan; Yağcıoğlu, A. Elif Anıl; Eni, Nurhayat; Karahan, Sevilay; Türkoğlu, İnci; Yıldız, Emine; Mercanlıgil, Seyit M.; Yazıcı, M. Kâzım

doi:10.1007/s00406-019-01016-x

Cited by 11 publications

(9 citation statements)

References 31 publications

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“…In patients with SMD, there is a high prevalence of three factors that are key to the development of a MetS: sedentary lifestyles, unbalanced dietary patterns and medication-induced weight gain [ 22 , 23 ]. As we have seen in our study, MetS without intervention increases with follow-up, similar to another study where MetS increased in a group of patients followed for 8 years [ 24 ]. Therefore, dietary modification can help to reduce the components of MetS, especially a reduction of fats (saturated, trans and cholesterol), sodium and sugars, which would help to prevent or control dyslipidemia, hyperglycemia and hypertension [ 25 ].…”

Section: Discussionsupporting

confidence: 91%

Metabolic impact of a nutrition education program for the promotion of fruit and vegetable consumption with people with severe mental disorders (DIETMENT)

et al. 2022

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Objectives The aim of this study is to determine the metabolic impact of a nutrition education program on metabolic parameters and the presence of metabolic syndrome (MetS). Results Seventy-four patients were included (mean age, 48.7 years [Standard deviation, SD: 10.8], 55.4% men). The diagnoses of SMD were 37.8% schizophrenia and related disorders; 29.7% bipolar disorder; 25.7% depressive disorder; 4.1% personality disorders; and 2.7% obsessive compulsive disorders. Thirty-seven individuals were distributed in both the intervention group (IG) and the control group (CG). In the IG the presence of MetS was 56.3% and in the CG 46.7%, with no statistically significant difference (p = 0.309). At the end of the study, glomerular filtrate decreased in the IG, body mass index and abdominal perimeter increased in both groups, and there were no changes in metabolic parameters between the groups. Between the baseline and the end of the study, there was no increase in the number of patients diagnosed with MetS (14 at both points); and in the CG the increase was from 8 to 12 (p = 0.005). An intervention based on fruit and vegetable intake could prevent progression to MetS in individuals with SMD, decreasing the likelihood of cardiovascular disease. Trial registration The trial was retrospectively registered on International Standard Randomised Controlled Trial Number (ISRCTN) Register on 11 March 2022 (ISRCTN12024347)

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Section: Discussionsupporting

confidence: 91%

Metabolic impact of a nutrition education program for the promotion of fruit and vegetable consumption with people with severe mental disorders (DIETMENT)

et al. 2022

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“…Применение антипсихотиков сопряжено с развитием ряда нежелательных двигательных эффектов, чаще которых развиваются акатизия -до 76 % [10,11] и метаболические нарушения -от 35 до 56 % [12].…”

Section: оригинальные исследованияunclassified

The effectiveness of treatment and features of adverse events in patients with schizophrenia receiving risperidone and haloperidol depending on the duration of illness

Kornetova¹,

Goncharova²,

Dmitrieva³

et al. 2021

Medical news of the North Caucasus

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“…Yazıcı ve arkadaşlarının 2011 yılında yayınladığı çalışmada kliniğimizde 319 şizofreni hastası metabolik sendrom açısından değerlendirilmiş, yaygınlığı ATP-III ölçütlerine göre %34,2, ATP-IIIA ölçütlerine göre %37, IDF ölçütlerine göre %41,7 olarak bildirilmiştir; bu hastalardan %32,6'sının klozapin kullandığı saptanmıştır. Bu çalışmanın devamı niteliğinde bir diğer çalışmada da bu hastaların arasından 149 şizofreni hastası ortalama 8 yıl sonra tekrar değerlendirilmiştir (Yoca ve ark. 2019).…”

Section: Introductionunclassified

Common Side Effects and Metabolic Syndrome due to Clozapine: Relationship with the Clinical Variables and Disability

Gürcan¹,

Şenol²,

Yağcıoğlu³

et al. 2020

Turkish Journal of Psychiatry

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Klozapine bağlı sık görülen yan etkiler tedavi sürecini olumsuz etkileyebilmektedir. Bu çalışmada klozapin kullanan şizofreni hastalarında sık görülen yan etkilerin değerlendirilmesi, metabolik sendrom yaygınlığının saptanması, klinik değişkenlerle ilişkisinin ve yetiyitimine etkisinin incelenmesi amaçlanmıştır. Yöntem: Çalışmaya DSM-IV'e göre şizofreni tanısı konulan, klozapin kullanmakta olan 122 hasta dahil edilmiştir. Hastadan ve hastane dosyasından alınan bilgiler doğrultusunda klinik bilgiler değerlendirilmiş, bedensel ölçümler ve laboratuvar değerleri kaydedilmiştir. Hastalara

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A follow-up study of metabolic syndrome in schizophrenia

Cited by 11 publications

References 31 publications

Metabolic impact of a nutrition education program for the promotion of fruit and vegetable consumption with people with severe mental disorders (DIETMENT)

Metabolic impact of a nutrition education program for the promotion of fruit and vegetable consumption with people with severe mental disorders (DIETMENT)

The effectiveness of treatment and features of adverse events in patients with schizophrenia receiving risperidone and haloperidol depending on the duration of illness

Common Side Effects and Metabolic Syndrome due to Clozapine: Relationship with the Clinical Variables and Disability

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