“…Again, reported methods of assessment varied, and conclusions may be limited by deficiencies in sample representativeness, random assignment to treatment alternatives, and objective and reliable assessment of symptomatic and functional status at study entry and completion. Despite these limitations, several reports noted reductions in morbidity, 29,[58][59][60][61][67][68][69]76,77,80,81,88,89 and improved social [60][61][62]67,70,71,76,79,85,88,89 and vocational 60,68,89 functioning. Several studies also concluded that medication compliance was enhanced by adjunctive educational and follow-up visits, or illness-related inability to assimilate or retain information.…”