A fortified corn/soy atole increases growth, decreases morbidity and improves nutritional status in urban Guatemalan toddlers and young children

Abstract

This study assessed growth, morbidity and nutritional biomarkers in toddlers and children receiving multiple micronutrients via a fortified corn/soy atole. Children 6–72 mo of age, n=1003, from six municipal nurseries in Guatemala City, GT were enrolled in a prospective, longitudinal study. Five d/wk for 10 mo children received Chispuditos®, a corn/soy atole beverage mix (18.8 g blended in 227 ml heated liquid), under the supervision of nursery staff. Chispuditos was fortified with 21 vitamins/minerals and provided 12 mg iron and 9 mg zinc per serving. Anthropometric data and morbidity were monitored every 2 mo and fasting venous blood samples obtained at baseline and end line. Growth rates increased (P<0.05) across all age groups (58% for children 6–23 mo, 87% 24–35 mo, 69% 36–59 mo, 80% 60–72 mo) when compared to similar aged children in the same nurseries the prior yr. After 10 mo the incidence of acute diarrhea and acute respiratory infections were lowered (61% and 71% decrease, respectively, p<0.05). End line hemoglobin, iron, transferrin, folic acid and vitamin B12 increased (P<.0.05) vs baseline. Zinc, ferritin and C‐reactive protein did not change. We conclude that Chispuditos is a culturally acceptable mechanism to provide multiple micronutrients and improve health and nutritional status in malnourished Guatemalan children. Supported by the Mathile Institute for the Advancement of Human Nutrition®.

The Effects of Multiple Micronutrient Fortified Beverage and Responsive Caregiving Interventions on Early Childhood Development, Hemoglobin, and Ferritin among Infants in Rural Guatemala

“…Chispuditos ® was developed by a team of nutrition scientists at the Mathile Institute for the Advancement of Human Nutrition and manufactured locally. Pre-post-acceptability studies with young children suggest high acceptance and daily adherence [22,[25][26][27]. The placebo for the study consisted of the same corn-soy blend fortified only with vitamin B2 (which has no known effect on the outcomes) that was otherwise identical to Chispuditos ® .…”