A Forward-planning Solution for the IMPORT HIGH Breast IMRT Trial

Techniques of tumour bed boost irradiation in breast conserving therapy: Current evidence and suggested guidelines

“…For tumour bed boost only, IMRT may not hold a great deal of advantage over conventional techniques as has been demonstrated in planning dosimetric studies [73]. However, IMRT due to its unique ability to deliver a simultaneous integrated boost (SIB) may be considered for whole breast and tumour bed boost [74].…”

“…The study arm in the trial involves delivery of radiation with forward planned IMRT portals in which the entire breast will be delineated into three groups: low dose breast volume, standard dose breast volume and tumour bed. The low dose breast volume would receive 36 Gy in 15 fractions, standard risk breast volume would receive 40 Gy in 15 fractions and the tumour bed would receive 48 Gy 0r 53 Gy with simultaneous integrated boost technique [74].…”