A fourteen-year retrospective of clinic-epidemiological aspects of cutaneous and visceral leishmaniasis in Uberlândia, Minas Gerais, Brazil

Abstract

ABSTRACT:The purpose of this study was to describe clinic-epidemiological characteristics of leishmaniasis cases attended at the Clinical Hospital of Federal University of Uberlândia (CHU), state of Minas Gerais, from January 2000 to December 2013. This is a descriptive and retrospective review of medical records of patients diagnosed with leishmaniasis and treated at the CHU. 168 cases of leishmaniasis were analyzed and most patients were male, aged 23 to 60 years. For cutaneous and mucosal leishmaniasis, single lesions, located mainly in lower limbs and head (CL) and nasal mucosa (ML), were the most common clinical presentation. Regarding the diagnosis, the most performed methods for CL and ML were biopsy plus histopathology and biopsy plus immunohistochemistry; biopsy plus direct parasitological examination methods were the most frequent for VL. Most patients (84%) received treatment, mainly glucantime for both CL and ML; VL treatment was based on amphotericin B or glucantime. According to data from Sistema de Informações de Agravos de Notificação (SINAN), the Brazilian information system to notify and investigate cases of diseases and their aggravations, no case has been confirmed as autochthonous. It is noteworthy the underreporting of cases and the lack of complete information in medical records. Our results may contribute to a better understanding of the real situation in Uberlândia region concerning to leishmaniasis.

Zoonoses Causadas Por Protozoários No Estado De Pernambuco: Uma Análise Epidemiológica

“…(2,0%) notificações respectivamente (Figura 1). A diversidade e ampla distribuição geográfica da fauna flebotomínea no estado de Pernambuco, contribui para a transmissão da LV (BRITO et al, 2012;SILVA et al, 2017) Com relação ao número de casos notificados por sexo é possível observar que para a maioria das doenças estudadas houve predomínio do sexo masculino, com prevalência de 69,5% para LV, 65,6% para LTA e 55,6% para malária (figura 2), corroborando com estudos realizados anteriormente, nos quais indicam que os homens representam o maior percentual de infectados por serem mais expostos em suas atividades diárias (VASCONCELOS et al, 2017;SILVA et al, 2021;ARAÚJO;NUNES, 2017;BRAZUNA et al, 2012;FARIA et al, 2019).…”

First epidemiological description of tegumentar and visceral Leishmaniasis in Patrocínio Municipality, Minas Gerais (2000-2017)

“…In another study in Minas Gerais (SILVA, 2017), cases of VL were initially treated with antimonial and replaced with amphotericin B (deoxycholate or liposomal) in the event of therapeutic failure. Araújo and Nunes (2017) observed that the most used treatment for TL in the cutaneous and mucosal forms was glucantime, alone or in combination with pentoxifylline, while treatment for VL was performed with amphotericin B or glucantime. In the present study, all victims were cured.…”