Building and managing digital collections or information resources for knowledge perseveration in academic institutions, especially tertiary institutions, has increasingly become more needful than ever before as many believe it remains the way out for sustainable academic teaching and learning in the 21st century. This belief stems from the fact that the 21st-century teaching and learning activities, as well as research, has already moved to a digital base, especially as the new normal, having witnessed the sudden emergence of coronavirus 19 with physical restrictions to buildings where physical collections are housed such as the library and other information centres. From the data collection stage to the research data analysis to the publication stage, knowledge preservation has fully embraced digital processes where Google forms, Survey Hearts and Monkeys are now used for building data. Questionnaires, interviews, and so many other instruments are now done through digital processes and mediums, thereby building the collection of knowledge in the digital format. The issue may not really be the processes of building the collections in the digital format, however, but the management of these digital collections in the digital format to preserve the knowledge for posterity via different databases and digital preservation processes. Therefore, this opinion paper is designed to explore different kinds of literature on this subject area of digital collections management to close the gap in this area of digital collections for a 21st-century academic institution and to proffer some recommendations with a special interest in institutional repositories moving fully into automated version. Therefore, the opinion of this paper is to review relevant literature to argue whether digital collections in academic institutions is the way out for sustainable development in the knowledge management aspect.