Abstract-The stochastic simulation of biological systems is an increasingly popular technique in Bioinformatics. It is often an enlightening technique, especially for multi-stable systems which dynamics can be hardly captured with ordinary differential equations. To be effective, stochastic simulations should be supported by powerful statistical analysis tools. The simulation-analysis workflow may however result in being computationally expensive, thus compromising the interactivity required in model tuning. In this work we advocate the high-level design of simulators for stochastic systems as a vehicle for building efficient and portable parallel simulators. In particular, the Calculus of Wrapped Components (CWC) simulator, which is designed according to the FastFlow's pattern-based approach, is presented and discussed in this work. FastFlow has been extended to support also clusters of multi-cores with minimal coding effort, assessing the portability of the approach.