A framework for modeling and simulating Aedes aegypti and dengue fever dynamics

Abstract

Dengue fever represents a great challenge for many countries, and methodologies to prevent and/or control its transmission have been largely discussed by the research community. Modeling is a powerful tool to understand epidemic dynamics and to evaluate costs, benefits and effectiveness of control strategies. In order to assist decision-makers and researchers in the evaluation of different methodologies, we developed DengueME, a collaborative open source platform to simulate dengue disease and its vector's dynamics. DengueME provides a series of compartmental and individual-based models, implemented over a GIS database, that represents the Aedes aegypti's life cycle, human demography, human mobility, urban landscape and dengue transmission. The platform is designed to allow easy simulation of intervention scenarios. A GUI was developed to facilitate model configuration and data input.

Simulação de Aplicação de Armadilhas no Combate ao Aedes aegypti

“…Em [Lima et al 2014]é apresentado um framework especializado na simulação do Aedes aegypti. Construído sobre o TerraMe com dados geográficos, o framework permite a construção de intervenções para auxiliar no combateà dengue.…”

“…Construído sobre o TerraMe com dados geográficos, o framework permite a construção de intervenções para auxiliar no combateà dengue. O framework leva em conta a simulação do ciclo de vida do mosquito, densidade demográfica humana, mobilidade humana, terreno da região e transmissão da dengue [Lima et al 2014]. Por outro lado, o framework não leva em conta a intervenção por armadilhas como especificada no presente artigo.…”

DengueME: A Tool for the Modeling and Simulation of Dengue Spatiotemporal Dynamics

“… Exponential growth of publications on dengue (blue circles) and specifically on dengue models (red squares) in the last two decades (search done in the ISI-Web of knowledge database) [ 63 ]. …”

“…( a ) Satellite image (Google Earth); ( b ) map of census tracts; ( c ) simulated map generated by DengueME. Highlighted blue areas are the sites of application of adulticide [ 63 ].…”

“…Comparison between the the vector population in the study area with and without the application of adulticide. ( a ) Global impact considering the entire study area; ( b ) local impact in a 100 × 100 m area [ 63 ].…”