A fuel-initiated DNA molecular machine for microRNA detection in serum <i>via</i> poly-adenine-mediated spherical nucleic acids

Gu, Menghan; Yi, Xiaoqing; Shang, Zhiwei; Nong, Xianliang; Lin, Meihua; Xia, Fan

doi:10.1039/d3tb02361c

J. Mater. Chem. B

2023

DOI: 10.1039/d3tb02361c

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A fuel-initiated DNA molecular machine for microRNA detection in serum via poly-adenine-mediated spherical nucleic acids

Menghan Gu,

Xiaoqing Yi,

Zhiwei Shang

et al.

Abstract: By combining polyA-mediated spherical nucleic acids with toehold mediated strand displacement reaction, a fuel-initiated DNA molecular machine has been constructed for sensitively and selectively detecting microRNA-22 in fetal bovine serum.

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A fuel-initiated DNA molecular machine for microRNA detection in serum via poly-adenine-mediated spherical nucleic acids

Abstract: By combining polyA-mediated spherical nucleic acids with toehold mediated strand displacement reaction, a fuel-initiated DNA molecular machine has been constructed for sensitively and selectively detecting microRNA-22 in fetal bovine serum.

Cited by 2 publications

References 63 publications

Highly sensitive and label-free immunoassay of chloramphenicol based on poly-adenine-mediated spherical nucleic acid and hybridization chain reaction amplification

Highly sensitive and label-free immunoassay of chloramphenicol based on poly-adenine-mediated spherical nucleic acid and hybridization chain reaction amplification

ECL and visual dual-mode detection of miRNA-21 based on HRP/Au NPs composite probe and CRISPR/Cas12a strategy

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