“…Feedstock issues include substrate type or composition (Kougias et al, 2013a(Kougias et al, , 2014bLienen et al, 2014;Subramanian and Pagilla, 2014;Moeller and Görsch, 2015;Moeller et al, 2015bMoeller et al, , 2016Lindorfer and Demmig, 2016); particle size and fibre content (Moeller et al, 2016;Van Weelden et al, 2016); and the presence of surface active agents such as oils and grease (Subramanian and Pagilla, 2014) or fulvic acid (Pognani et al, 2017). Process or operational factors may include high organic loading rate (overloading) or inconsistent feed to the digester (Ganidi et al, 2011;Kougias et al, 2013aKougias et al, , 2013bKougias et al, , 2014bKougias et al, , 2014cKougias et al, , 2015bMoeller and Görsch, 2015;Moeller et al, 2012aMoeller et al, , 2015aMoeller et al, , 2015bSuhartini et al, 2014); digester configuration (Ganidi et al, 2009) or mixing intensity and pattern (Subramanian and Pagilla, 2014;Kougias et al, 2014b;Subramanian et al, 2015); temperature changes (Siebels and Long, 2013;Kougias et al, 2014b;Moeller and Görsch, 2015;Lindorfer and Demmig, 2016;Moestedt et al, 2017); and abrupt degassing or viscosity changes (Moeller et al, 2012b(Moeller et al, , 2015bLindorfer and Demmig, 2016).…”