2024
DOI: 10.1002/psp4.13222
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A fully automatic tool for development of population pharmacokinetic models

Xiaomei Chen,
Rikard Nordgren,
Stella Belin
et al.

Abstract: Population pharmacokinetic (PK) models are widely used to inform drug development by pharmaceutical companies and facilitate drug evaluation by regulatory agencies. Developing a population PK model is a multi‐step, challenging, and time‐consuming process involving iterative manual model fitting and evaluation. A tool for fully automatic model development (AMD) of common population PK models is presented here. The AMD tool is implemented in Pharmpy, a versatile open‐source library for pharmacometrics. It consis… Show more

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