A functional bimodal mesoporous silica nanoparticle with redox/cellulase dual-responsive gatekeepers for controlled release of fungicide

Abstract

Integrating toxic fungicide into a functional stimuli-responsive nanosystem can effectively improve the fungus control specificity and reduce the effect on non-target organisms. We report here a redox and cellulase dual-responsive multifunctional nanoparticle based on bimodal mesoporous silica (BMMs) to deliver prochloraz (Pro) for the smart management of wilt disease (Pro-AC-SS-BMMs, known as P-ASB). The surface of the nanocarrier was modified with an aminosilane coupling agent, and Pro was encapsulated by physical adsorption using 2,2′-dithiodiacetic acid as a smart bridge and disulfide (SS) cross-linked aminocellulose (AC) as gatekeepers. P-ASB nanoparticles (NPs) had a spherical structure, and the size was 531.2 ± 4.9 nm. The loading rate of Pro was 28.5%, and the NPs possessed excellent redox/cellulase dual-responsive release characteristics in the presence of glutathione (GSH) and cellulase. The nanocarrier could effectively protect Pro against photodegradation and had better foliar wettability than the Pro technical. Fluorescence tracer results showed that the nanocarriers were taken up and activated by the mycelium. P-ASB NPs had better control efficacy against Rhizoctonia solani and had no significant toxicity to cells and bacteria. This study provides a new strategy for enhancing the environmental protection and promoting the development of green agriculture.

Synthesis of organic–inorganic hybrid nanocomposites modified by catalase-like catalytic sites for the controlling of kiwifruit bacterial canker

“…Whereas, composite nanomaterials by reasonable designed can improve the antibacterial effect, systemic effect in plant and biocompatibility, so as to improve the protective activity and curative activity of plant diseases in vivo. [34][35][36] Hence, proposing a novel design strategy of composite nanomaterials for the effective prevention and control of kiwifruit canker holds immense promise for managing plant diseases.…”

A dual pesticide–fertilizer silicon-base nanocomposite to synergistically control fungal disease and provide nutrition

“…27 However, Pro has poor water solubility and is very sensitive to light. 28 Hymexazol (Hym) is a systemic fungicide and soil disinfectant, as well as a plant growth regulator, that can not only effectively inhibit the growth of pathogenic fungi mycelium but also promote the development of crop roots. 29,30 In this study, a pH-responsive degradable dual pesticide bimetallic fertilizer nanoparticle (Pro@Cu-MSNs-ZnO/Hym) was constructed.…”