A further breakthrough in biphasic, rhodium-catalyzed hydroformylation: the use of Per(2,6-di-O-methyl)-β-cyclodextrin as inverse phase transfer catalyst

High‐Pressure 31P{1H} NMR Studies of RhH(CO)(TPPTS)3 in the Presence of Methylated Cyclodextrins: New Light on Rhodium‐Catalyzed Hydroformylation Reaction Assisted by Cyclodextrins

“…For example, the randomly methylated-b-cyclodextrin (RAME-b-CD) that is a cheap, non-toxic and bulk commercially available compound allowed one to achieve the hydroformylation of longchain olefins with an initial turnover frequency and aldehyde selectivity of 300 h À1 and 95%, respectively, while avoiding the formation of emulsions and the partition of the rhodium catalyst between the organic and aqueous phases. [7] Unfortunately, the normal to branched aldehydes ratio was always lower than that observed without a mass-transfer promoter (1.8 vs. 2.7 without cyclodextrin). [8] This unexpected decrease in the normal to branched aldehydes ratio is the major drawback of the cyclodextrin-based hydroformylation process as the linear aldehyde is the more desired product.…”

Fast Aqueous/Organic Hydrogenation of Arenes, Olefins and Carbonyl Compounds by Poly(N‐Vinylpyrrolidone)‐Ru as Amphiphilic Microreactor System

“…[27] Here, the PVP-Ru amphiphilic microreactor system was successfully used in the hydrogenation of terminal higher olefins and cycloolefins in the aqueous/organic system. Although the TOF decreased with increasing the chain length of olefins, the TOF of the extremely water-insoluble 1-hexadecene reached 3000 h À 1 (entries 7 -11).…”

Biphasic Aqueous Organometallic Catalysis Promoted by Cyclodextrins: How to Design the Water‐Soluble Phenylphosphane to Avoid Interaction with Cyclodextrin

“…[4] Among the different CDs used, the randomly methylated b-CD (Rame-b-CD) appeared to be the most efficient (Table 1). [5] Indeed, Rame-b-CD notably increased the reaction rates, while avoiding the formation of an emulsion and the partition of the catalyst between the organic and aqueous phases. Nevertheless, this b-CD derivative forms an inclusion complex with the TPPTS ligand.…”