A Gastroschisis-Like Abdominal Wall Defect in the Left Hypochondrium. Case Report and Literature Review

Melikoğlu, Mustafa; Karagüzel, Güngör; Öğüş, Mehmet; Aslan, Abdurrahman; İnan, Mustafa

doi:10.1055/s-2008-1071119

Cited by 14 publications

(10 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We have only found two similar cases described previously as a gastroschisis‐like abdominal wall defect [Melikoğlu et al, 1998], and as an unusual left‐sided abdominal‐wall defect recently published [Fraser and Crabbe, 2002]. The abdominal wall defect of these two cases, has a location similar to that of our case, but both are unilateral affecting the left side.…”

Section: Discussionsupporting

confidence: 75%

“…The differences with gastroschisis are obvious, not only in their localization but in the implicated structures. This type of defect must be very infrequent, since we have identified only two similar reports in the literature [Melikoğlu et al, 1998; Fraser and Crabbe, 2002]. For these reasons, we describe the defect in detail and provide a speculative discussion based on the embryology of abdominal wall anomalies and their possible pathogeneses.…”

Section: Introductionmentioning

confidence: 93%

See 1 more Smart Citation

Unusual congenital abdominal wall defect and review

Carrera

Pitarch

García

et al. 2003

American J of Med Genetics Pt A

View full text Add to dashboard Cite

Abdominal wall defects distant from the umbilicus are very unusual. We describe a patient with a congenital defect adjacent and external to the lateral border of the recti muscles, rounded in shape, bilateral and symmetrical, but affecting different structures in each side, musculocutaneous agenesis in the left side and only muscle agenesis in the right one. The morphologic characteristics of the defect and the absence of associated anomalies, suggest that this anomaly may be the result of an event acting during phenogenesis. We consider that this defect is different from other structural abnormalities of the anterior abdominal wall which occur much earlier at certain periods of the embryogenesis. Though the etiology is speculative, we could postulate a disruptive origin of the defect of unknown cause.

show abstract

Section: Discussionsupporting

confidence: 75%

Section: Introductionmentioning

confidence: 93%

Unusual congenital abdominal wall defect and review

Carrera

Pitarch

García

et al. 2003

American J of Med Genetics Pt A

View full text Add to dashboard Cite

show abstract

“…In the 2 previous reports, the defects were relatively small and situated in the left upper quadrant. In the present patient the defect was rather large and situated in the left flank; the edges of the defect were well developed and fibrous and the surrounding muscles were normal unlike in another report (4) in which the left flank muscles were deficient.…”

Section: Discussioncontrasting

confidence: 72%

“…Gastroschisis is an abdominal wall defect (AWD), which usually occurs on the right side of the umbilical cord, but may occur on the left side (1,7,8). Left-sided AWD distant from the umbilical cord is rare and only 2 cases (3,4) have been reported by the end of 2002. This is a report of a rare left-sided AWD.…”

Section: Introductionmentioning

confidence: 99%

A Rare Left-Sided Abdominal Wall Defect

Ameh

Mshelbwala²,

Sabiu³

2004

Eur J Pediatr Surg

View full text Add to dashboard Cite

show abstract

“…In another scenario, the primary intestinal loop may herniate normally into the umbilical cord, with another part of the gut tube herniating through an unclosed portion of the body wall. The more lateral ventral wall defects [Melikoğlu et al, 1998; Fraser and Crabbe, 2002; Carrera et al, 2003; Ameh et al, 2004] that are not adjacent to the umbilical cord have been proposed to be due to an abnormality in the migration of the lateral plate mesoderm (specifically the parietal layer). These lateral ventral wall defects allow the internal organs to either bulge, covered by a thin membrane or normal skin, or eviscerate.…”

Section: Current Embryologic Hypotheses: Pathogenesismentioning

confidence: 99%

Development of gastroschisis: Review of hypotheses, a novel hypothesis, and implications for research

Feldkamp

Carey

Sadler

2007

American J of Med Genetics Pt A

198

204

View full text Add to dashboard Cite

Gastroschisis, a ventral body wall defect, is a continuing challenge and concern to researchers, clinicians, and epidemiologists seeking to identify its cause(s) and pathogenesis. Concern has been renewed in recent years because, unlike most other birth defects, rates of gastroschisis are reportedly increasing in many developed and developing countries. No tenable explanation or specific causes have been identified for this trend. Rates of gastroschisis are particularly high among pregnancies of very young women. Such an intriguing association, not observed to this degree with other birth defects, may afford clues to the defect's cause. Understanding the causes of gastroschisis may provide insight to the defect's origin. In pursuing such causal studies, it would be helpful to understand the embryogenesis of gastroschisis. To date, four main embryologic hypotheses have been proposed: (1) Failure of mesoderm to form in the body wall; (2) Rupture of the amnion around the umbilical ring with subsequent herniation of bowel; (3) Abnormal involution of the right umbilical vein leading to weakening of the body wall and gut herniation; and (4) Disruption of the right vitelline (yolk sac) artery with subsequent body wall damage and gut herniation. Although based on embryological phenomena, these hypotheses do not provide an adequate explanation for how gastroschisis would occur. Therefore, we propose an alternative hypothesis, based on well described embryonic events. Specifically, we propose that abnormal folding of the body wall results in a ventral body wall defect through which the gut herniates, leading to the clinical presentation of gastroschisis. This hypothesis potentially explains the origin of gastroschisis as well as that of other developmental defects of the ventral wall.

show abstract

A Gastroschisis-Like Abdominal Wall Defect in the Left Hypochondrium. Case Report and Literature Review

Cited by 14 publications

References 2 publications

Unusual congenital abdominal wall defect and review

Unusual congenital abdominal wall defect and review

A Rare Left-Sided Abdominal Wall Defect

Development of gastroschisis: Review of hypotheses, a novel hypothesis, and implications for research

Contact Info

Product

Resources

About