Effect of confinement (wall proximity) of a confined impinging jet reactor (CIJR) on the flow field, residence time distribution and heat transfer are explored, through experiments and CFD simulations. Hydrodynamic characteristics are evaluated for different parameters namely confinement, impinging jet velocity, temperature gradient, and so on. For 2 mm confinement, highest values of dispersion number and overall heat transfer coefficient are observed due to interaction of turbulent eddies followed by the effect of reactor wall proximity. For the CIJR having confinements above 10 mm, jet velocity need to be greater than 3 m/s to achieve both, excellent mixing efficiency and high heat removal rate. Empirical correlations for Dispersion and Nusselt numbers as a function of Rej and L/D are obtained, over a range of 500≤italicRej≤3000 and 5≤L/D≤35, which correspond to jet velocity of 0.5–3 m/s. The present study gives a basis for designing CIJR suitable for rapid, homogeneous, exothermic reactions.