1995
DOI: 10.1055/s-1995-5007
|View full text |Cite
|
Sign up to set email alerts
|

A General Method for the Synthesis of Bridged Indole Alkaloids. Addition of Carbon Nucleophiles to N-Alkylpyridinium Salts

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
38
0

Year Published

1999
1999
2017
2017

Publication Types

Select...
8
1

Relationship

2
7

Authors

Journals

citations
Cited by 96 publications
(38 citation statements)
references
References 0 publications
0
38
0
Order By: Relevance
“…(1), Figure 1]. [7a] Given the great importance of indole-containing triarylmethanes [8] and the challenge for the synthesis of optically active unsymmetrical triarylmethanes, we recently found that the synthesis of unsymmetrical triarylmethanes could be obtained through a Brønsted acid (1) catalyzed FriedelCrafts alkylation of (3-indolyl)methanamine with another electron-rich arene [Eq. (2), Figure 1].…”
Section: Introductionmentioning
confidence: 99%
“…(1), Figure 1]. [7a] Given the great importance of indole-containing triarylmethanes [8] and the challenge for the synthesis of optically active unsymmetrical triarylmethanes, we recently found that the synthesis of unsymmetrical triarylmethanes could be obtained through a Brønsted acid (1) catalyzed FriedelCrafts alkylation of (3-indolyl)methanamine with another electron-rich arene [Eq. (2), Figure 1].…”
Section: Introductionmentioning
confidence: 99%
“…88,89 Given the importance of indole derivatives in biology, [90][91][92] The same group has also studied the oxidative kinetic resolution of sec-alcohols using chiral Pd(II)-NHC complexes and molecular oxygen as a oxidant. [93][94][95] As an example, the axially chiral Pd(II)-NHC complex 29 was tested in the oxidative kinetic resolution of a wide range of sec-alcohols affording the corresponding alcohols in moderate conversions (48-68%) and moderate to high ee's (53-94%).…”
Section: Methodsmentioning
confidence: 99%
“…4 Among them, 2-indolylmethanamine derivatives are particularly important because of their ubiquitous presence in numerous biologically active compounds. [5][6][7][8][9] Therefore, methods for a general, rapid, and regioselective preparation of 2-indolyl-methanamines would be highly desirable. Zhou et al 10 successfully reported a Rh III -catalyzed regioselective addition of indole C−H bonds to aryl-and alkyl-N-sulfonylimines for the preparation of 2-indolyl-methanamine derivatives with good functional group tolerance, but in relatively low yields (between 42 to 71%, see Scheme 1).…”
Section: Introductionmentioning
confidence: 99%