A general synthetic route to [Cu(X)(NHC)] (NHC = N-heterocyclic carbene, X = Cl, Br, I) complexes

Abstract

A series of complexes of the type [Cu(X)(NHC)] (X = I, Br, Cl, NHC = N-heterocyclic carbene) was synthesised using a one-pot, mild and user-friendly (aerobic, tech. grade solvents) procedure.

A stereoselective access to a ferrocene-based planar chiral triazolium salt

“…[17] The presence of copper(I) bound carbene was evidenced by 13 Å, similar to those in related neutral [(NHC)CuCl] complexes. [17] M A N U S C R I P T…”

Synthesis, characterization and catalytic activity of stable [(NHC)H][ZnXY2] (NHC =N-Heterocyclic carbene, X, Y = Cl, Br) species

“…Recently, NHC complexes of gold(I) and copper(I) have been synthesized by reacting the corresponding imidazol(in)ium salts with the metal precursors in the presence of K 2 CO 3 in air under mild conditions [8,9]. Based on these reports, attempts towards the synthesis of Zn(II)-NHC complexes were carried out using a similar strategy (Scheme 1) [10].…”

“…Compounds 1-3 are considered analogues to the metallate intermediates obtained during the synthesis of Au(I)-and Cu(I)-NHC complexes via the reaction of NHC salts with gold and copper precursors in the absence of a base [8,9]. In order to generate a library of zincate salts that we could later use to generate the Zn(II)-complexes, we reacted various imidazol(in)ium salts with ZnCl 2 and ZnBr 2 in the absence of base (Scheme 2).…”

Copper N-Heterocyclic Carbene Complexes As Active Catalysts for the Synthesis of 2-Substituted Oxazolines from Nitriles and Aminoalcohols

“…In the presence of Na 2 CO 3 , increasing the amount of 2a leads to a drop in conversion (Table 1, entries 6-8) while an opposite effect is witnessed when using NaOAc (Table 1, entries 9-11). Different copper-NHC complexes 21 were then tested in order to activate the nitrile (Table 2). Gratifyingly, these complexes achieved moderate to good conversion depending on the nature of the NHC ligand (Table 2, entries 1-4).…”