A Genotype-Phenotype Model for Predicting Resistance Training Effects
on Leg Press Performance
Tao Mei,
Yanchun Li,
Xiaoxia Li
et al.
Abstract:This study develops a comprehensive genotype-phenotype model for predicting the effects of resistance training on leg press performance. A cohort of physically inactive adults (N=193) underwent 12 weeks of resistance training, and measurements of maximum isokinetic leg press peak force, muscle mass, and thickness were taken before and after the intervention. Whole-genome genotyping was performed, and genome-wide association analysis identified 85 novel SNPs significantly associated with changes in leg press st… Show more
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