A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation

Squillaro, Anthony I.; Chow, Monica D.; Arias, Fernando D.; Sadimin, Evita; Lee, Yi Horng

doi:10.3389/fped.2020.00404

Cited by 6 publications

(5 citation statements)

References 22 publications

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“…The tumor can be completely resected under laparoscopy.When a patient is admitted to the hospital due to torsion of the greater omentum, laparoscopic exploration can be performed in the emergency department, both laparoscopic tumor resection and the greater omentum resection can be performed at the same time. According to previous reports in the literature, the recurrence rate after resection is <5%, mainly due to incomplete resection (17).…”

Section: Discussionmentioning

confidence: 91%

Primary Omental Lipoma in a Child: A Case Report and Literature Review

2022

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BackgroundLipoma is a common benign tumor derived from adipose tissue, with an incidence of nearly 10%. It is the most common mesenchymal tumor throughout the body. However, the pathogenesis of lipoma is not clear yet, and the increased incidence is attributable to obesity, elevated serum cholesterol, diabetes, trauma, radiation, familial predisposition, and chromosome. Primary omental tumor is a rare lipoma occurring in the greater omentum, most of which is reported in the form of clinical case reports. Nevertheless, primary omental tumor is even rarer in children. To date, there have been few reports of clinical cases.Case PresentationWe report a rare case of primary omental lipoma in a 6-year-old boy. After an accidental fall, a CT scan found that he had a tumor in the left upper abdomen. He had no history of abdominal pain, abdominal mass, vomiting, etc. The boy was admitted to the hospital within 3 days, and was diagnosed with an intra-abdominal tumor. After admission, abdominal ultrasound and enhanced CT showed a 71 ×40 ×60 mm mass in the left middle abdomen, which was considered a lipoma. There was no abnormality in tumor markers. Through laparoscopic surgery, intraoperative exploration revealed that the tumor was located in the left mid-upper abdomen, and was yellow, solid, soft, and isolated. The intraoperative diagnosis was an omental lipoma. We used an ultrasonic knife to resect the omentum close to the base of the tumor. The tumor was completely resected, put in a retrieval bag and sealed. Finally, the left and right sides of the umbilical incision were extended to take out the tumor tissue. The child received liquid food 6 h after the operation and was discharged 3 days later. The postoperative pathological diagnosis was an omental lipoma. He was seen at follow-up 3 months after discharge and had no complaints, an abnominal ultrasound showed no tumor recurrence.ConclusionPrimary omental lipoma in children is a rare benign tumor of the omentum. Its etiology and pathology are not clear. US, CT, and MRI can facilitate clinical diagnosis and preoperative evaluation. Laparoscopic surgery is an effective treatment, and the prognosis of children is favorable. This case is beneficial to improve the clinical knowledge of pediatric surgeons about this rare disease.

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Section: Discussionmentioning

confidence: 91%

Primary Omental Lipoma in a Child: A Case Report and Literature Review

2022

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“…Some studiesrevealed extremities are the most common site (61%) and this is followed by trunk (15%), abdomen (14%) and in head and neck region (11%) whereas, other studies demonstrated a preponderance of the tumor site is in the trunk (44%-48%) and these may also arise in the spine, mediastinum, lungs, trunk, mesentery, peritoneal cavity, retro peritoneum and inguinal canal 1,8,3,9,10,11,12,13,14 .Among them abdominal lipoblastomas which are uncommon comprising around 7% of all reported lipoblastomas and most commonly found in the retroperitoneum. Only less than 15 reported cases abdominal lipoblastoma were noticed to arise in the mesentery 15,16 .We report such a rare childhood soft tissue tumor that was noticed in the abdomen of a 2 years female child presented with huge abdominal distension along with intermittent abdominal pain. Exploratory laparotomy revealed a giant intraabdominal mesenteric mass and both histopathological and immunohistochemistry jointly reported this as a case of lipoblastoma.…”

Section: Introductionmentioning

confidence: 83%

A Giant Mesentric Lipoblastoma in a Two-Year Girl: A Case Report

Palit

Chakroborty

Saha

et al. 2021

J Shaheed Suhrawardy Med Coll

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Back ground: Abdominal lipoblastomas which are benign but uncommon soft tissue tumors in children rarely arise from the mesentery.However, benign, these may attain in large size and cause compression symptoms. Complete resection and close post-operative monitoring are necessary for avoidance of recurrence. Histopathology with immunohistochemistry in conjunction with the morphology is the gold standard for diagnosis. Herein such a rare a case of mesenteric lipoblastoma with huge abdominal distention is reported. Case presentation: A 2-year-old girl presented with an enormous abdominal swelling occupying almost all quadrants of the abdomen with repeated dull abdominal pain. The swelling was a non-tender and tensely cystic. USG and CT Scan could not distinguish the proper origin or location of the mass but demonstrated as a large encapsulated and lobulated fatty mass measuring about (16.4x10.0x18.6cm) involving right hypochondriac, epigastric, bilateral ilio-lumber, umbilical & hypogastric regions, pushing the bowel loops upward & laterally with mild mesenteric thickening of perilesional mesentery and separated from the liver & both kidneys and other intraabdominal organs. After exploratory laparotomy there revealed a well capsuled large (about 15x11x14cm)soft yellow mass displacing the entire intra-abdominal contents, connected by a single vascular pedicle with the mesentery and loosely enclosing the mesentery as a whole. Histology and immunohistochemistry of completely resected mass conûrmed the presence of mature adipocytes and immuno-morphology was compatible with Lipoblastoma. Conclusion: This case represents one of the largest mesenteric lipoblastomas in accordance to the patient’s age that histologically, mostly composed of mature adipocytes with few lipoblasts. J Shaheed Suhrawardy Med Coll, December 2020, Vol.12(1); 54-57

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“…A review included 263 cases (13 case series) of lipoblastoma with a median age at presentation of 22.6 months [ 10 ], and a 1.7:1 male-to-female ratio, which indicates a slight male predominance [ 8 , 10 ]. Abdominal lipoblastomas are rare; around 7% of all lipoblastomas and the majority of them develop retroperitoneally [ 6 , 11 , 12 ]. Lipoblastoma occurs in 80% of cases, whereas lipoblastomatosis occurs in 20% of cases [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

“…Lipoblastoma occurs in 80% of cases, whereas lipoblastomatosis occurs in 20% of cases [ 13 ]. Lipoblastoma and lipoblastomatosis are benign and do not have a risk to metastasize or undergo malignant transformation [ 1 , 3 , 4 , 6 , 13 ], the natural history of an unresected lipoblastoma may be maturing into a lipoma [ 4 , 6 , 11 ]. The recurrence rate reported ranges from 13% to 46% in seven case series [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

A Giant Compressive Mesenteric Lipoblastoma Initially Suspected to Be Abdominal Malignancy: A Report of a Rare Case in a Nine-Month-Old Infant

S¹,

Choridah²,

Lau³

et al. 2023

Cureus

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Lipoblastoma is a rare benign soft tissue neoplasm rising from embryonic white adipose tissue known as lipoblast that keeps proliferating during the postnatal period. Although lipoblastomas are benign, they often grow rapidly. Most lipoblastomas are asymptomatic at presentation; they can present as a growing painless palpable mass and progressive symptoms of various organ compression depending on localization. A giant mesenteric lipoblastoma is a rare case with only a few cases reported. An infant with large intraabdominal masses may present preoperative diagnostic difficulties. Differential diagnoses are broad and may include sarcomas, germ-cell tumors, lipomas, lymphomas, hepatoblastomas, Wilm’s tumors, and neuroblastomas. Thorough clinical, radiological, and pathological investigations are ultimately required to obtain a definitive diagnosis. Regardless of location, the treatment of choice for lipoblastoma is complete surgical resection. All patients should be followed up for a minimum of five years We report a rare case of a giant compressive mesenteric lipoblastoma that was initially suspected as abdominal malignancy in a nine-month-old infant. As physicians, we must always consider the underlying cause as well as the malignant or benign nature of a growing mass to treat the patient appropriately.

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A Giant Childhood Mesenteric Lipoblastoma With Extensive Maturation

Cited by 6 publications

References 22 publications

Primary Omental Lipoma in a Child: A Case Report and Literature Review

Primary Omental Lipoma in a Child: A Case Report and Literature Review

A Giant Mesentric Lipoblastoma in a Two-Year Girl: A Case Report

A Giant Compressive Mesenteric Lipoblastoma Initially Suspected to Be Abdominal Malignancy: A Report of a Rare Case in a Nine-Month-Old Infant

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