A giant plexiform schwannoma of the brachial plexus: case report

Kohyama, Sho; Hara, Yuki; Nishiura, Yasumasa; Hara, Tetsuya; Nakagawa, Tatsuo; Ochiai, Naoyuki

doi:10.1186/1749-7221-6-9

Cited by 13 publications

(23 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In these presentations, schwannoma expression is often diffuse and localizes to multiple nerves and nerve fascicles. 9,10 Multinodular or plexiform schwannomas with multifascicular involvement have also been well described. 9,10 The expression of multiple schwannomas arising in a serial pattern from a single nerve fascicle may represent a presentation of a linear variant of segmental schwannomatosis.…”

Section: Discussionmentioning

confidence: 99%

A Linear Variant of Segmental Schwannomatosis Localized to the Upper Extremity

Shaterian

Özyürekoğlu

2022

Journal of Hand and Microsurgery

View full text Add to dashboard Cite

Introduction Schwannomas represent benign peripheral nerve sheath tumors. Their phenotypic presentations in schwannomatosis and segmental schwannomatosis have been well described. To date, however, cases of schwannomatosis or multiple schwannomas localized to a single nerve fascicle have been limited in the literature. Case Presentation In this study, we identify a case of a 48 year-old non-neurofibromatosis male who presented with symptomatic schwannomas localized to a single nerve fascicle of the upper extremity. Intraoperative exploration revealed four schwannomas arising from a 15-cm segment of ulnar nerve fascicle. Surgical excision was successful, without neurological deficit or recurrence. Conclusion This study identifies a case of schwannomatosis localized to a single nerve fascicle that may represent a linear variant of segmental schwannomatosis. The presentation may represent a temporary linear appearance in progression to “nonlinear” segmental variant; however, a molecularly distinct subset of schwannomas cannot be excluded.

show abstract

Section: Discussionmentioning

confidence: 99%

A Linear Variant of Segmental Schwannomatosis Localized to the Upper Extremity

Shaterian

Özyürekoğlu

2022

Journal of Hand and Microsurgery

View full text Add to dashboard Cite

show abstract

“…In the group of tumours originating from small nerve branches, 2 tumours showed growth pattern of plexiform schwannoma and 1 of cellular schwannoma. Plexiform schwannoma is a rare variant accounting for about 5% of all schwannomas [ 41 ]. It can be associated with neurofibromatosis type 2 or schwannomatosis; however, unlike plexiform neurofibroma, it is not linked to neurofibromatosis type 1.…”

Section: Discussionmentioning

confidence: 99%

“…It can be associated with neurofibromatosis type 2 or schwannomatosis; however, unlike plexiform neurofibroma, it is not linked to neurofibromatosis type 1. Similarity between these 2 types of tumours is based on their multinodular growth pattern [ 41 ]. Cellular schwannoma shows features of nuclear atypia.…”

Section: Discussionmentioning

confidence: 99%

Results of Surgical Treatment of Schwannomas Arising from Extremities

Gosk

Gutkowska

Urban

et al. 2015

BioMed Research International

View full text Add to dashboard Cite

Schwannomas are benign neoplasms derived from Schwann cells. In this work, we present our experience in operative management of schwannomas and analyse results of treatment. Clinical material consisted of 34 patients, in whom 44 schwannomas located in extremities were excised between 1985 and 2013. Thirty-five tumours originated from major peripheral nerves and 9 from small nerve branches. Postoperatively, in the first group of tumours, pain resolved in 100%, paresthesias in 83.3%, and Hoffmann-Tinel sign in 91.6% of the patients. Improvement in motor function was noted in 28.5% of the cases, in sensory function: complete in 70%, and partial in 15%. The most frequently affected major peripheral nerves were the ulnar (11 tumours) and median (5 tumours) nerves. Schwannomas originating from small nerve branches were removed without identification of the site of origin. After their resection, definitive healing was achieved. Conclusions. (1) Schwannomas located in extremities arise predominantly from major peripheral nerves, most commonly the ulnar and median nerves. (2) Gradual tumour growth causes exacerbation of compression neuropathy, creating an indication for surgery. (3) In most cases, improvement in peripheral nerve function after excision of schwannoma is achieved. (4) The risk of new permanent postoperative neurological deficits is low.

show abstract

“…Schwannoma is a benign, encapsulated, slow growing, neural neoplasm of Schwann cell origin [6]. Plexiform schwannoma is a rare variant of schwannoma that accounts for only 5% of all schwannomas, with a plexiform or multinodular growth pattern which may or may not be apparent macroscopically [2] [7] [8]. It is usually found on the trunk, head, neck and upper extremities most often involving the skin and subcutaneous tissues.…”

Section: Discussionmentioning

confidence: 99%

“…the body [1]. Plexiform schwannoma is a rare variant of schwannoma that accounts for only 5% of all schwannomas, and typically shows a plexiform or multinodular growth pattern [2]. It was first described by Harkin and Reed in 1978 [3], and very few cases had since been reported.…”

Section: Introductionmentioning

confidence: 99%

Plexiform Schwannoma: A Report of Two Unusual Cases, and a Review of the Literature

Ali¹,

Vassiliou²,

Stenhouse³

2014

OJST

View full text Add to dashboard Cite

Plexiform schwannoma is a benign tumour arising from the sheath of myelinated nerve fibres that may occur in any part of the body. It is very rare in the head and neck region and poses diagnostic challenges. Here we present two unusual cases. The first is about a fifteen-year-old boy with a large plexiform schwannoma in the right retro maxillary region, extending up to but not invading the orbit. Initial cytology reported it as a pleomorphic adenoma, but histological findings after excision confirmed it to be a benign plexiform schwannoma. A zygomatic osteotomy was required to excise the tumour in its entirety. The second reported case is about solitary lesion on the tongue of a 46-year-old Chinese man, clinically mimicking a mucocoele. This case report highlights the diagnostic challenges posed by plexiform schwannoma, and the role of imaging and cytopathology, as well as the importance of definitive histopathological analysis. It also describes the surgical management of these lesions, and provides a review of the literature, in particular of cases occurring in the head and neck region.

show abstract

A giant plexiform schwannoma of the brachial plexus: case report

Cited by 13 publications

References 7 publications

A Linear Variant of Segmental Schwannomatosis Localized to the Upper Extremity

A Linear Variant of Segmental Schwannomatosis Localized to the Upper Extremity

Results of Surgical Treatment of Schwannomas Arising from Extremities

Plexiform Schwannoma: A Report of Two Unusual Cases, and a Review of the Literature

Contact Info

Product

Resources

About