Road vehicles using gasoline, a gasoline-electric hybrid, diesel, methane, hydrogen, and a hydrogen-electric hybrid were investigated for differences in energy consumption as a function of driving behavior and vehicle characteristics. The results show that driving behavior has a large impact on energy consumption of vehicles in real traffic. Forceful acceleration events were linked with increased energy consumption, while moderate acceleration and steady average speed were linked with energy consumption benefits. In vehicles with regenerative braking, the frequency of forceful braking events is linked with a statistically significant lesser energy consumption as energy is generated for the vehicle during those events. The tested hydrogen-and methane-powered vehicles were found to have the overall best results regarding energy consumption.