“…Among these, a significant proportion, comprising 1–10%, are classified as toxic while the majority exhibit varying degrees of edibility, presenting either medicinal or nutritional interest and importance. Over 200 genera of macrofungi feature species are either used as food sources or appreciated for their potential health benefits [ 1 , 2 , 3 ]. These species can be found either cultivated or among the wild flora of different areas over the world, and their broad spectrum of high- and low-molecular-weight bioactive metabolites (belonging to classes of compounds such as the alkaloids, lipids, phenols, polysaccharides, proteins, peptides, steroids, lectins, and terpenoids) can be responsible for a large variety of therapeutic effects such as anti-inflammatory, antimicrobial, hepatoprotective, cytotoxic, antioxidant, antiviral, antifungal, and hypocholesterolemic effects [ 1 , 3 ].…”