A green approach to crosslinked polymer microspheres with undoped methacrylate monomers and their potential application as dental restorative materials

Abstract

Herein, a green approach to crosslinked polymer microspheres with undoped methacrylate monomers is presented. The protocol is set up by means of photoinitiated precipitation polymerization of a trifunctional crosslinker, i.e. trihydroxymethyl propane trimethyl acrylate (TMPTMA) and methyl methacrylate (MMA) for the purpose of achieving pure and crosslinked microspheres. The evolution of photoinitiated precipitation polymerization is tracked and the formation mechanism of poly(TMPTMA-MMA) microspheres is also elucidated. Finally, the potency of so-obtained crosslinked microspheres is explored to serve as organic fillers in dental restorative materials.Scheme 1 Illustration of the formation of microspheres via photoinitiated precipitation polymerization of TMPTMA and MMA with AIBN as initiator.This journal is

Preparation and modification of PS–PMMA microspheres and their application in high performance liquid chromatography

“…Currently, polymeric microspheres are mainly used in high performance liquid chromatography (HPLC) as a stationary phase, and their surface is modied with certain functional groups to provide them with certain properties. The common substrates of polymer microspheres are polystyrene (PS), 1 polymethyl methacrylate (PMMA), 2 and poly(glycidyl methacrylate) (PGMA), 3,4 which are widely used in HPLC columns due to their reactivity, low cost, acid and base resistance, and biocompatibility. 5 PS microspheres have good sphericity, high specic surface area, uniform microspheres, controllable particle size, and a very active benzene ring that is reactive to a series of functional groups (e.g., -OH, -COOH, NH, -CHO, etc.).…”